Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug 1;60(252):714-717.
doi: 10.31729/jnma.7624.

Typhoid Fever among Patients Diagnosed with Dengue in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Affiliations

Typhoid Fever among Patients Diagnosed with Dengue in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Arun Kumar Mahato et al. JNMA J Nepal Med Assoc. .

Abstract

Introduction: Dengue and typhoid fever are different entities with overlapping signs and symptoms which are indistinguishable and there have been few reports of co-infections from endemic areas. The resemblance of symptoms makes accurate clinical diagnosis and treatment difficult. Both are major health problems mainly during monsoon and co-infection, if not timely diagnosed and treated can be fatal. The aim of this study was to find out the prevalence of typhoid fever among patients diagnosed with dengue at a tertiary care centre.

Methods: A descriptive cross-sectional study was done among patients of age >15 years with dengue fever attending the medicine outpatient department in a tertiary care centre from 1 July 2021 to 30 June 2022. Ethical approval was taken from the Institutional Review Committee (Reference number: 466/2020). Convenience sampling was used. Patients with other risk factors for febrile illness were excluded from the study. Point estimate and 90% Confidence Interval were calculated.

Results: Among 95 dengue cases, typhoid fever was observed in 18 (18.95%) (12.36-25.54, 90% Confidence Interval). The mean age of presentation was 35±9 years with a male to female ratio of 0.8:1. Fever was the most common presentation with a mean temperature of 100.8±2.1°F.

Conclusions: The prevalence of typhoid fever among dengue-positive cases was higher as compared to other studies done in similar settings.

Keywords: dengue; fever; typhoid fever.

PubMed Disclaimer

Conflict of interest statement

None.

Figures

Figure 1
Figure 1. The common presentation of typhoid fever among patients diagnosed with dengue (n= 18).

Similar articles

Cited by

References

    1. Buckle GC, Walker CL, Black RE. Typhoid fever and paratyphoid fever: systematic review to estimate global morbidity and mortality for 2010. J Glob Health. 2012 Jun;2(1):010401. doi: 10.7189/jogh.01.010401. - DOI - PMC - PubMed
    1. Green S, Rothman A. Immunopathological mechanisms in dengue and dengue hemorrhagic fever. Curr Opin Infect Dis. 2006 Oct;19(5):429–36. doi: 10.1097/01.qco.0000244047.31135.fa. - DOI - PubMed
    1. Blacksell SD, Sharma NP, Phumratanaprapin W, Jenjaroen K, Peacock SJ, White NJ, et al. Serological and blood culture investigations of Nepalese fever patients. Trans R Soc Trop Med Hyg. 2007 Jul;101(7):686–90. doi: 10.1016/j.trstmh.2007.02.015. - DOI - PubMed
    1. World Health Organization. Dengue guidelines, for diagnosis, treatment, prevention and control [Internet]. Geneva (CH): World Health Organization; 2009. [2009 April 21; ]. [2022 June 24; ]. https://www.who.int/publications/i/item/9789241547871 Available from:
    1. Sa-Ngamuang C, Haddawy P, Luvira V, Piyaphanee W, Iamsirithaworn S, Lawpoolsri S. Accuracy of dengue clinical diagnosis with and without NS1 antigen rapid test: Comparison between human and Bayesian network model decision. PLoS Negl Trop Dis. 2018 Jun 18;12(6):e0006573. doi: 10.1371/journal.pntd.0006573. - DOI - PMC - PubMed

LinkOut - more resources