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. 2023 Mar;37(2):550-555.
doi: 10.1111/jvim.16634. Epub 2023 Jan 28.

Prevalence of signs of lower urinary tract disease and positive urine culture in dogs with diabetes mellitus: A retrospective study

Valerie Nelson  1 , Amy Downey  2 , Stacie Summers  3 , Sarah Shropshire  1
Affiliations

Prevalence of signs of lower urinary tract disease and positive urine culture in dogs with diabetes mellitus: A retrospective study

Valerie Nelson et al. J Vet Intern Med. 2023 Mar.

Abstract

Background: No recent studies have evaluated the association between clinical signs of lower urinary tract disease (LUTD) and positive urine culture in dogs with diabetes mellitus.

Objective: Determine the prevalence of subclinical bacteriuria (ie, positive urine culture without signs of LUTD) in dogs with diabetes mellitus.

Animals: One hundred seven dogs with diabetes mellitus were evaluated at a university veterinary hospital.

Methods: Retrospective study evaluating diabetic dogs with a single sample paired urinalysis and urine culture. Relationship between the presence of signs of LUTD, pyuria, and bacteriuria and urine culture results were compared using Fisher exact testing.

Results: Fifteen dogs (14%) had a positive urine culture via cystocentesis or free catch, of which 8 (53%) had pyuria, and 4 (27%) had signs of LUTD. Of the 88 dogs (82%) without signs of LUTD, 11 (13%) had a positive culture. A significant association was found between a positive urine culture and pyuria (OR infinity; 95% CI 20.34-infinity, P < .00001) and bacteriuria (OR infinity; 95% CI 164.4-infinity, P < .00001). No association was found between urine culture results and signs of LUTD (OR 1.87; 95% CI 0.59-6.85, P = .46).

Conclusion and clinical importance: Subclinical bacteriuria occurred in this cohort of dogs, and our findings reinforce the recommendation that urine cultures should not be routinely performed in diabetic dogs particularly if pyuria and bacteriuria are absent.

Keywords: antibiotics; bacteriuria; canine; urinalysis; urinary tract infection.

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Conflict of interest statement

Authors declare no conflict of interest.

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References

    1. Forrester SD, Troy GC, Dalton MN, Huffman JW, Holtzman G. Retrospective evaluation of urinary tract infection in 42 dogs with hyperadrenocorticism or diabetes mellitus or both. J Vet Intern Med. 1999;13:557‐560. - PubMed
    1. McGuire NC, Schulman R, Ridgway MD, et al. Detection of occult urinary tract infections in dogs with diabetes mellitus. J Am Anim Hosp Assoc. 2002;38:541‐544. - PubMed
    1. Diehl KJ. Long‐term complications of diabetes mellitus, part II: gastrointestinal and infectious. Vet Clin North Am Small Anim Pract. 1995;25:731‐751. - PubMed
    1. Weese JS, Blondeau JM, Boothe D, et al. Antimicrobial use guidelines for treatment of urinary tract disease in dogs and cats: antimicrobial guidelines working group of the international society for companion animal infectious diseases. Vet Med Int. 2011;4:1‐9. - PMC - PubMed
    1. McGhie JA, Stayt J, Hosgood GL. Prevalence of bacteriuria in dogs without clinical signs of urinary tract infection presenting for elective surgical procedures. Aust Vet J. 2014;92:33‐37. - PubMed