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Review
. 2023 Mar-Apr:119-120:1-2.
doi: 10.1016/j.exphem.2023.01.004. Epub 2023 Jan 26.

Transfusions with laboratory-grown red blood cells: a new development in science

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Free article
Review

Transfusions with laboratory-grown red blood cells: a new development in science

Lakshmi Venkata Simhachalam Kutikuppala et al. Exp Hematol. 2023 Mar-Apr.
Free article

Abstract

It is inevitable to anticipate the development of laboratory abilities and their involvement in clinical research in a fast-paced world. The RESTORE study is one such incident that has drawn the interest of various specialists. Red blood cells (RBCs) that have been generated in a laboratory have been transfused into a volunteer in this trial. To our knowledge, this procedure was the first to deliver laboratory-grown cells to another individual through a blood transfusion, which is an advancement in laboratory innovations. The purpose of the research was to determine how long a mini-transfusion of up to two teaspoons or 10 mL of laboratory-grown RBCs will persist in the body in comparison with an equivalent quantity of regular cells from the same donor. Assuming the process can be scaled up to a standard transfusion, this approach is advantageous because it can address the shortage of donors for those with rare blood types. Laboratory-grown blood cells are anticipated to last longer and perform better, which is another benefit to be noticed. This study represents a tremendous advancement in scientific innovation and teamwork while providing high-quality care to those who need it the most, although additional trials are required before clinical usage.

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Conflict of interest statement

Conflicts of Interest Disclosure The authors do not have any conflicts of interest to declare in relation to this work.

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