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Review
. 2023 Jan 11:13:1039529.
doi: 10.3389/fneur.2022.1039529. eCollection 2022.

Traumatic neuromas of peripheral nerves: Diagnosis, management and future perspectives

Hu Yang  1 , Yanzhao Dong  1 , Zewei Wang  2 , Jingtian Lai  2 , Chenjun Yao  2 , Haiying Zhou  1 , Ahmad Alhaskawi  1 , Sohaib Hasan Abdullah Ezzi  2 , Vishnu Goutham Kota  2 , Mohamed Hasan Abdulla Hasan Abdulla  2 , Hui Lu  1   3
Affiliations
Review

Traumatic neuromas of peripheral nerves: Diagnosis, management and future perspectives

Hu Yang et al. Front Neurol. .

Abstract

Traumatic neuromas are infrequent in clinical settings but are prevalent following trauma or surgery. A traumatic neuroma is not a true malignancy, rather, it is a hyperplastic, reparative nerve reaction after injury and typically manifests as a nodular mass. The most common clinical manifestations include painful hypersensitivity and the presence of a trigger point that causes neuralgic pain, which could seriously decrease the living standards of patients. While various studies are conducted aiming to improve current diagnosis and management strategies via the induction of emerging imaging tools and surgical or conservative treatment. However, researchers and clinicians have yet to reach a consensus regarding traumatic neuromas. In this review, we aim to start with the possible underlying mechanisms of traumatic neuromas, elaborate on the diagnosis, treatment, and prevention schemes, and discuss the current experiment models and advances in research for the future management of traumatic neuromas.

Keywords: clinical management; diagnosis; hand surgery; peripheral nerve; traumatic neuroma.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(A) Longitudinal and transverse ultrasound images of the left traumatic neuroma of the superficial branch of the radial nerve; (B) longitudinal and transverse images of the neuroma; (C, D) traumatic neuroma of the superficial branch of the radial nerve of the left wrist.
Figure 2
Figure 2
Cases of surgical management in four patients suffering from traumatic neuromas. (A) A 32-year-old female patient with a 2-year history of painful mass on the radial side of the right wrist; (B) a traumatic neuroma of the middle finger in a 34-year-old female patient as a result of previous finger tope amputation, (C) a 24-year-old patient with a traumatic neuroma on the wrist, (D) 33-year-old female presented a left index finger traumatic neuroma with local radiation pain for half a month, the patient had a history of left index finger injury by scissors several years ago.
Figure 3
Figure 3
A general summary of surgical methods for traumatic neuromas. Blue boxes indicate conventional methods and purple boxes indicate novel methods.
See this image and copyright information in PMC

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