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Editorial
. 2022 Nov 29;2(7):865-868.
doi: 10.1016/j.jacasi.2022.09.003. eCollection 2022 Dec.

TAVR in Nonagenarians: What the World May Learn From Japan

Jonathan Curio  1 , Ozan M Demir  2
Affiliations
Editorial

TAVR in Nonagenarians: What the World May Learn From Japan

Jonathan Curio et al. JACC Asia. .
No abstract available

Keywords: J-TVT registry; Japan; TAVR; elderly.

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Conflict of interest statement

The authors have reported that they have no relationships relevant to the content of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
Outcomes for Nonagenarians: J-TVT Registry vs Other International Studies Comparison of 30-day and 1-year mortality in the J-TVT registry compared with other large international studies in nonagenarians. Differences in mortality rates between studies are probably caused by variance in underlying nonagenarian population comorbidities, risk profile, and selection bias.
Figure 2
Figure 2
Current and Future Transcatheter Aortic Valve Replacement Research in Nonagenarians Current focus of transcatheter aortic valve replacement (TAVR) research in nonagenarians with aortic stenosis (AS) is based on registries. These are hampered by comparison with younger patient cohorts and survival and selection bias. Potential future research, thus, must aim to not only report observed outcomes but to better understand what might be generalizable patient selection criteria. This should incorporate frailty of patient scores and selection algorithms that aim to identify potential future fragility and, furthermore, to render such outcome predictions more precisely, not only hard endpoints, but also quality of life measures.
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References

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