Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Mar;601(5):887-888.
doi: 10.1113/JP284242. Epub 2023 Feb 6.

Regulation of PKD2 channel by TACAN: how does it link to cystogenesis in autosomal dominant polycystic kidney disease?

Maulana A Empitu  1   2 , Ika N Kadariswantiningsih  1   2
Affiliations
Free article
Comment

Regulation of PKD2 channel by TACAN: how does it link to cystogenesis in autosomal dominant polycystic kidney disease?

Maulana A Empitu et al. J Physiol. 2023 Mar.
Free article
No abstract available

Keywords: ADPKD; PKD2; TACAN; calcium signalling; cystogenesis; medicine; polycystin.

PubMed Disclaimer

Comment on

  • Regulation of PKD2 channel function by TACAN.
    Liu X, Zhang R, Fatehi M, Wang Y, Long W, Tian R, Deng X, Weng Z, Xu Q, Light PE, Tang J, Chen XZ. Liu X, et al. J Physiol. 2023 Jan;601(1):83-98. doi: 10.1113/JP283895. Epub 2022 Dec 13. J Physiol. 2023. PMID: 36420836

References

    1. Arif Pavel, M., Lv, C., Ng, C., Yang, L., Kashyap, P., Lam, C., Valentino, V., Fung, H. Y., Campbell, T., & Møller, S. G. (2016). Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant. Proceedings of the National Academy of Sciences, USA, 113(17), E2363-E2372.
    1. Brill, A. L., & Ehrlich, B. E. (2020). Polycystin 2: A calcium channel, channel partner, and regulator of calcium homeostasis in ADPKD. Cell Signaling, 66, 109490.
    1. Chebib, F. T., Sussman, C. R., Wang, X., Harris, P. C., & Torres, V. E. (2015). Vasopressin and disruption of calcium signalling in polycystic kidney disease. Nature Reviews. Nephrology, 11(8), 451-464.
    1. Cornec-Le Gall, E., Torres, V. E., & Harris, P. C. (2018). Genetic complexity of autosomal dominant polycystic kidney and liver diseases. Journal of the American Society of Nephrology, 29(1), 13-23.
    1. Liu, X., Zhang, R., Fatehi, M., Wang, Y., Long, W., Tian, R., Deng, X., Weng, Z., Xu, Q., & Light, P. E. (2022). Regulation of the PKD2 channel function by TACAN. The Journal of Physiology, 601(1), 83-98.

Publication types

Substances

LinkOut - more resources