Endothelin signalling drives dermal sheath smooth muscle contraction for hair follicle regression
- PMID: 36717628
- DOI: 10.1038/s41556-022-01077-6
Endothelin signalling drives dermal sheath smooth muscle contraction for hair follicle regression
Comment on
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Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression.Nat Cell Biol. 2023 Feb;25(2):222-234. doi: 10.1038/s41556-022-01065-w. Epub 2023 Jan 30. Nat Cell Biol. 2023. PMID: 36717629 Free PMC article.
References
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- Heitman, N. et al. Dermal sheath contraction powers stem cell niche relocation during hair cycle regression. Science 367, 161–166 (2020). This paper identifies the dermal sheath as a smooth muscle that contracts to drive hair follicle regression and reunite niche and stem cells for hair regrowth. - DOI - PubMed
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- Martino, P. A., Heitman, N. & Rendl, M. The dermal sheath: an emerging component of the hair follicle stem cell niche. Exp. Dermatol. 30, 512–521 (2021). A review article that discusses dermal sheath anatomy, highlights the emerging importance of the sheath in the hair follicle stem-cell niche, and examines potential therapeutic applications in hair regeneration and wound healing. - DOI - PubMed
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