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. 1987 Sep;57(3):343-50.

Renal effects of prednisolone in the chicken

J Springate  1 , D Jeffery, M Acara
Affiliations
  • PMID: 3671884

Renal effects of prednisolone in the chicken

J Springate et al. Res Commun Chem Pathol Pharmacol. 1987 Sep.

Abstract

The effects of prednisolone on renal tubular transport of organic ions, urine flow and glomerular filtration rate were studied using the Sperber preparation in chickens. Low infusion rates of 1 and 5 nmole/min prednisolone slightly enhanced organic ion excretion. At higher infusion rates up to 1,000 nmol/min, no change in organic ion transport was observed. Urine flow and glomerular filtration rate increased at prednisolone infusion rates of 50 nmole/min and higher, independent of changes in renal blood flow.

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