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Review
. 2023 Apr 1;36(2):67-73.
doi: 10.1097/QCO.0000000000000902. Epub 2023 Jan 25.

Community-acquired skin and soft-tissue infections in people who inject drugs

Fatima Allaw  1 , Johnny Zakhour, Souha S Kanj
Affiliations
Review

Community-acquired skin and soft-tissue infections in people who inject drugs

Fatima Allaw et al. Curr Opin Infect Dis. .

Abstract

Purpose of review: The aim of this review is to discuss the latest evidence of the epidemiology, microbiology, risk factors, diagnosis and management of community-acquired skin and soft tissue infections (SSTIs) in people who inject drug (PWID).

Recent findings: SSTIs are common complications in PWID and a major cause of morbidity and mortality. Infections can range from uncomplicated cellulitis, to abscesses, deep tissue necrosis and necrotizing fasciitis. They are predominantly caused by Gram-positive pathogens in particular Staphylococcus aureus and Streptococcus species; however, toxin-producing organisms such as Clostridium botulism or Clostridium tetani should be considered. The pathogenesis of SSTI in the setting of intravenous drug use (IDU) is different from non-IDU related SSTI, and management often requires surgical interventions in addition to adjunctive antibiotics. Harm reduction strategies and education about safe practices should be implemented to prevent morbidity and mortality as well as healthcare burden of SSTI in PWID.

Summary: Prompt diagnosis and proper medical and surgical management of SSTI will improve outcomes in PWID.

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References

    1. Key substance use and mental health indicators in the United States: results from the 2020 National Survey on Drug Use and Health. 2020; 156.
    1. Monteiro J, Phillips KT, Herman DS, et al. Self-treatment of skin infections by people who inject drugs. Drug Alcohol Depend 2020; 206:107695.
    1. Koshy JC, Bell B. Hand infections. J Hand Surg Am 2019; 44:46–54.
    1. Figgatt MC, Salazar ZR, Vincent L, et al. Treatment experiences for skin and soft tissue infections among participants of syringe service programs in North Carolina. Harm Reduct J 2021; 18:80.
    1. Hrycko A, Mateu-Gelabert P, Ciervo C, et al. Factors associated with severe bacterial infections in people who inject drugs: a single-center observational study. J Addict Med 2022.

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