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Case Reports
. 2023 Mar;40(3):271-275.
doi: 10.1111/echo.15529. Epub 2023 Jan 31.

Papillary muscle ventricular ectopy ablation in a malignant mitral valve prolapse: Ablation in Malignant Mitral Valve Prolapse: Ablation in Malignant Mitral Valve Prolapse

Sergio Conti  1 , Francesco Sabatino  1 , Carlo Caserta  2 , Giuseppe Sgarito  1
Affiliations
Case Reports

Papillary muscle ventricular ectopy ablation in a malignant mitral valve prolapse: Ablation in Malignant Mitral Valve Prolapse: Ablation in Malignant Mitral Valve Prolapse

Sergio Conti et al. Echocardiography. 2023 Mar.

Abstract

Patients with mitral valve prolapse (MVP) have a heterogeneous clinical spectrum, ranging from benign to severe clinical presentations such as sudden cardiac death (SCD). Some of the markers of "arrhythmic MVP" include inverted/biphasic T-waves, QT prolongation, and polymorphic premature ventricular contractions (PVCs) originating from the left ventricular outflow tract and papillary muscles (PMs). The genesis of arrhythmias in MVP recognizes the combination of the substrate (fibrosis) and the trigger (mechanical stretch). Therefore, ablation of ventricular arrhythmias originating from PMs in a patient with MVP can be considered an adjunctive strategy to lower the arrhythmic burden and reduce the risk of ICD shocks.

Keywords: catheter ablation; mitral annular disjunction; mitral valve prolapse; premature ventricular contractions; sudden cardiac death; ventricular fibrillation; ventricular tachycardia.

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References

REFERENCES

    1. Muthukumar L, Jahangir A, Jan MF, et al. Association between malignant mitral valve prolapse and sudden cardiac death: a review. JAMA Cardiol. 2020;5(9):1053-1061.
    1. Basso C, Iliceto S, Thiene G, Perazzolo Marra M. Mitral valve prolapse, ventricular arrhythmias, and sudden death. Circulation. 2019;140:952-964.
    1. Lancellotti P, Garbi M. Malignant mitral valve prolapse. Substrates to ventricular remodeling and arrhythmias. Circ Cardiovasc Imaging. 2016;9(8):e005248.
    1. Vahanian A, Beyersdorf F, Praz F, et al. 2021 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. 2022;43(7):561-632.
    1. Sabbag A, Essayagh B, Ramirez Barrera JD, et al. EHRA expert consensus statement on arrhythmic mitral valve prolapse and mitral annular disjunction complex in collaboration with the ESC Council on valvular heart disease and the European Association of Cardiovascular Imaging endorsed cby the Heart Rhythm Society, by the Asia Pacific Heart Rhythm Society, and by the Latin American Heart Rhythm Society. Europace. 2022;24(12):1981-2003.

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