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. 2023 Jan-Mar;26(1):17-22.
doi: 10.4103/aca.aca_290_20.

Cardiac myxomas: A single-center case series of 145 patients over a 32-year period study

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Cardiac myxomas: A single-center case series of 145 patients over a 32-year period study

Michopanou Nektaria et al. Ann Card Anaesth. 2023 Jan-Mar.

Abstract

Background: Myxomas are the most common primary cardiac tumors that develop mostly at the atrial chambers of the heart and represent 0,25% of all cardiac diseases.

Methods: This is a retrospective study aiming to analyze epidemiological and intraoperative data from cardiac myxoma cases in the hospital of the last 32 years. The study population was 145 cardiac surgical patients and was divided into 4 certain 8-year periods. 87,6% of cases had the myxoma located at left atrium and 97,2% of all patients fully recovered. 4,1% of patients relapsed and underwent a redo operation.

Results: Mean CPB time and mean ICU length of stay increased during the 8-year periods (p < 0,001, P < 0,001, P = 0,002 and P = 0,003 respectively). In-hospital length of stay decreased to 5 days in the most recent period (p < 0,001). Cases significantly increased to 54 in the last 8-year period (p = 0,009).

Conclusion: Improvement on cardiac imaging and a better accessibility may drive patients to earlier and safer diagnosis of myxomas preventing any deterioration of their condition. Improvement on postoperative care can also reduce in-hospital length of stay. Surgical excision is the treatment of choice and guaranteed survival at 97,2% of patients.

Keywords: Cardiac imaging techniques; cardiopulmonary by-pass; in-hospital length of stay; left atrium myxoma.

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Conflict of interest statement

There are no conflicts of interest.

References

    1. Goldberg HP, Glenn F, Dotter CT, Steinberg I. Myxoma of the left atrium; diagnosis made during life with operative and post-mortem findings. Circulation. 1952;6:762–7. - PubMed
    1. Keeling IM, Oberwalder P, Anelli-Monti M, Schuchlenz H, Demel U, Tilz GP, et al. Cardiac myxomas: 24 years of experience in 49 patients. Eur J Cardiothorac Surg. 2002;22:971–7. - PubMed
    1. Reynen K. Cardiac myxomas. N Engl J Med. 1995;333:1610–7. - PubMed
    1. Bertherat J. Carney complex (CNC) Orphanet J Rare Dis. 2006;1:21. - PMC - PubMed
    1. Stratakis C. Mutations of the gene encoding the protein kinase A type I-α regulatory subunit (PRKAR1A) in patients with the “Complex of spotty skin pigmentation, myxomas, endocrine overactivity, and schwannomas” (Carney complex) Ann N Y Acad Sci. 2002;968:3–21. - PubMed