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Case Reports
. 2023 Feb;20(2):320-324.
doi: 10.1513/AnnalsATS.202206-561CC.

A Shocking Case of Shock

Affiliations
Case Reports

A Shocking Case of Shock

William Leon et al. Ann Am Thorac Soc. 2023 Feb.
No abstract available

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Figures

Figure 1.
Figure 1.
Physical examination on admission was notable for periorbital ecchymosis and significant subconjunctival hemorrhage bilaterally. There was no evidence of hemotympanum, periauricular ecchymosis, or rhinorrhea, and follow-up head computed tomography without contrast was unremarkable.
Figure 2.
Figure 2.
Computed tomography angiography of the chest demonstrated bilateral basilar predominant ground-glass opacities with consolidations and small bilateral pleural effusions. There was no evidence of pulmonary emboli.
Figure 3.
Figure 3.
The patient’s bedside monitor demonstrated a profound change in blood pressure by arterial waveform monitor four minutes after treatment. Note that the cuff pressure had not been recycled yet, demonstrating the previous blood pressure. The only intervention between these two time points was a single injection of 50 mg diphenhydramine into a peripheral IV catheter. IV = intravenous.
Figure 4.
Figure 4.
Diagnostic algorithm for the mast cell activation disorders. Adapted by permission from Reference . AHNMD = associated hematologic non-mast cell lineage disease; IgE = immunoglobulin E; KIT = tyrosine protein kinase; MCA = mast cell activation; MCAD = mast cell activation disorder; MCAS = mast cell activation syndrome; MMAS = monoclonal mast cell activation syndrome; SM = systemic mastocytosis; WHO = World Health Organization.

References

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    1. Gotlib J, Kluin-Nelemans HC, George TI, Akin C, Sotlar K, Hermine O, et al. Efficacy and safety of midostaurin in advanced systemic mastocytosis. N Engl J Med . 2016;374:2530–2541. - PubMed

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