Treatment of herpes simplex keratitis with idoxuridine and vidarabine: a double-blind study
- PMID: 367239
Treatment of herpes simplex keratitis with idoxuridine and vidarabine: a double-blind study
Abstract
A double controlled clinical study comparing idoxuridine (IDU) and vidarabine (ara-A) in the treatment of uncomplicated herpes simplex keratitis was carried out with 10 patients. No statistically significant differences occurred in the healing time between IDU (6.8 days) and ara-A (8.0 days). Two moderately adverse reactions to IDU were observed, but no demonstrable ocular toxicity was noted with ara-A.
Similar articles
-
Ara-A and IDU therapy of human superficial herpetic keratitis.Invest Ophthalmol. 1975 Oct;14(10):762-3. Invest Ophthalmol. 1975. PMID: 1102484 Clinical Trial.
-
Vidarabine therapy of simple and IDU-complicated herpetic keratitis.Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1976 Sep-Oct;81(5):813-25. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1976. PMID: 798369 Clinical Trial.
-
[Adenine-arabinoside in the treatment of idu-resistant herpes simplex keratitis (author's transl)].J Fr Ophtalmol. 1979 Mar;2(3):205-7. J Fr Ophtalmol. 1979. PMID: 156754 French.
-
[Arabinosyladenine in ophthalmology (author's transl)].J Fr Ophtalmol. 1981;4(6-7):525-30. J Fr Ophtalmol. 1981. PMID: 7028853 Review. French.
-
Therapy for human herpesvirus infections. A perspective.Ala J Med Sci. 1985 Apr;22(2):193-207. Ala J Med Sci. 1985. PMID: 2988359 Review. No abstract available.
Cited by
-
Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.Cochrane Database Syst Rev. 2015 Jan 9;1(1):CD002898. doi: 10.1002/14651858.CD002898.pub5. Cochrane Database Syst Rev. 2015. PMID: 25879115 Free PMC article.
-
A review of antiviral drugs and other compounds with activity against feline herpesvirus type 1.Vet Ophthalmol. 2016 Jul;19 Suppl 1(Suppl 1):119-30. doi: 10.1111/vop.12375. Epub 2016 Apr 19. Vet Ophthalmol. 2016. PMID: 27091747 Free PMC article. Review.
-
The treatment of herpes simplex virus epithelial keratitis.Trans Am Ophthalmol Soc. 2000;98:505-32. Trans Am Ophthalmol Soc. 2000. PMID: 11190039 Free PMC article.
-
Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. doi: 10.1002/14651858.CD002898.pub4. Cochrane Database Syst Rev. 2010. Update in: Cochrane Database Syst Rev. 2015 Jan 09;1:CD002898. doi: 10.1002/14651858.CD002898.pub5. PMID: 21154352 Free PMC article. Updated.