Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Mar;42(3):379-382.
doi: 10.1007/s10096-023-04559-z. Epub 2023 Feb 2.

Clinical significance of concomitant bacteriuria in patients with Staphylococcus aureus bacteraemia

Matthaios Papadimitriou-Olivgeris  1   2 , Damien Jacot  3 , Laurence Senn  4   5 , Benoit Guery  5
Affiliations

Clinical significance of concomitant bacteriuria in patients with Staphylococcus aureus bacteraemia

Matthaios Papadimitriou-Olivgeris et al. Eur J Clin Microbiol Infect Dis. 2023 Mar.

Abstract

This retrospective study, conducted at Lausanne University Hospital (2015-2021), compared Staphylococcus aureus bacteraemia (SABA) patients with or without concomitant bacteriuria (SABU). Among 448 included bacteraemic patients, 62 (13.8%) had S. aureus concurrently isolated from urine. In multivariate analysis, there was a significant difference in the odds of community-onset bacteraemia (P 0.030), malignancy (P 0.002), > 1 pair of positive blood cultures (P 0.037), and persistent bacteraemia for at least 48 h (P 0.045) in patients with concurrent SABU. No difference concerning mortality was found. On the other hand, SABU was associated with higher rates of SABA recurrence after antibiotic cessation.

Keywords: Bacteraemia; Bacteriuria; Bloodstream infection; Infective endocarditis; Staphylococcus aureus.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flowchart of included patients
See this image and copyright information in PMC

References

    1. Karakonstantis S, Kalemaki D. The clinical significance of concomitant bacteriuria in patients with Staphylococcus aureus bacteremia. Rev Meta-Anal Infect Dis. 2018;50(9):648–659. - PubMed
    1. Choi SH, Lee SO, Choi JP, Lim SK, Chung JW, Choi SH, Jeong JY, Woo JH, Kim YS. The clinical significance of concurrent Staphylococcus aureus bacteriuria in patients with S. aureus bacteremia. J Infect. 2009;59(1):37–41. doi: 10.1016/j.jinf.2009.05.002. - DOI - PubMed
    1. Papadimitriou-Olivgeris M, Monney P, Mueller L, Senn L, Guery B. The LAUsanne STAPHylococcus aureus ENdocarditis (LAUSTAPHEN) score: a prediction score to estimate initial risk for infective endocarditis in patients with S. aureus bacteremia. Front Cardiovasc Med. 2022;9:961579. doi: 10.3389/fcvm.2022.961579. - DOI - PMC - PubMed
    1. Papadimitriou-Olivgeris M, Senn L, Bertelli C, Grandbastien B, Steinmetz S, Boillat-Blanco N. Prevalence and factors associated with prosthetic joint infections in patients with Staphylococcus aureus bacteraemia: a 7-year retrospective study. Antibiotics. 2022;11(10):1323. doi: 10.3390/antibiotics11101323. - DOI - PMC - PubMed
    1. Asgeirsson H, Kristjansson M, Kristinsson KG, Gudlaugsson O. Clinical significance of Staphylococcus aureus bacteriuria in a nationwide study of adults with S. aureus bacteraemia. J Infect. 2012;64(1):41–46. doi: 10.1016/j.jinf.2011.10.009. - DOI - PubMed

MeSH terms