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. 2023 Apr 1;42(4):e122-e124.
doi: 10.1097/INF.0000000000003810. Epub 2022 Dec 29.

Increase in Invasive Group a Streptococcal Infections in Children in the Netherlands, A Survey Among 7 Hospitals in 2022

Evelien B van Kempen  1 , Patricia C J Bruijning-Verhagen  2 , Dorine Borensztajn  3   4 , Clementien L Vermont  5 , Marjolijn S W Quaak  5 , Jo-Anne Janson  6 , Ianthe Maat  7 , Kim Stol  8 , Bart J M Vlaminckx  9 , Jantien W Wieringa  10 , Nina M van Sorge  11   12 , Navin P Boeddha  3 , Mirjam van Veen  1
Affiliations

Increase in Invasive Group a Streptococcal Infections in Children in the Netherlands, A Survey Among 7 Hospitals in 2022

Evelien B van Kempen et al. Pediatr Infect Dis J. .

Abstract

Following an increase in notifiable invasive group A streptococcal (iGAS) infections in the Netherlands, we conducted a survey among 7 hospitals. Pediatric iGAS case numbers were 2-fold higher between July 2021 and June 2022 versus pre-COVID-19. A sharp increase occurred early 2022, most pronounced in <5 years old and for diagnoses empyema and necrotizing fasciitis. This recent pediatric iGAS surge warrants investigation and vigilance.

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Conflict of interest statement

N.M.v.S. declares royalties related to a patent (WO 2013/020090 A3) on vaccine development against Streptococcus pyogenes (Vaxcyte; Licensee: University of California San Diego with N.M.v.S. as co-inventor). The other authors have no conflicts of interest to disclose.

References

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    1. Dutch College of General Practitioners (Nederlands Huisartsen Genootschap). Communication: Increase in invasive group A streptococcal infections mainly in young children (Toename invasieve infecties groep A streptokokken vooral bij jonge kinderen). 2022. Available at: https://www.nhg.org/actueel/nieuws/toename-invasieve-infecties-groep-str... . Accessed August 25, 2022.
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