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. 2023 Jun 1;136(6):1030-1038.
doi: 10.1213/ANE.0000000000006336. Epub 2023 May 19.

Failure to Rescue and Mortality Differences After Appendectomy in a Low-Middle-Income Country and the United States

Eric B Rosero  1 , Javier Eslava-Schmalbach  2 , Nathaly Garzón-Orjuela  2 , Giancarlo Buitrago  3 , Girish P Joshi  1
Affiliations

Failure to Rescue and Mortality Differences After Appendectomy in a Low-Middle-Income Country and the United States

Eric B Rosero et al. Anesth Analg. .

Abstract

Background: Major disparities in complications and mortality after appendectomy between countries with different income levels have not been well characterized, as comparative studies at patient level between countries are scant. This study aimed to investigate variations in postoperative complications, mortality, and failure to rescue after appendectomy between a high-income country and a low-to-middle-income country.

Methods: Hospital discharges on adult patients who underwent appendectomy were extracted from administrative databases from Colombia and 2 states of the United States (Florida and New York). Outcomes included major postoperative complications, in-hospital mortality, and failure to rescue. Univariate analyses were conducted to compare outcomes between the 2 countries. Multivariable logistic regression analyses were conducted to examine the independent effect of country on outcomes after adjustment for patient age, sex, comorbidity index, severity of appendicitis, and appendectomy route (laparoscopic/open).

Results: A total of 62,338 cases from Colombia and 57,987 from the United States were included in the analysis. Patients in Colombia were significantly younger and healthier but had a higher incidence of peritonitis. Use of laparoscopy was significantly lower in Colombia (5.9% vs 89.4%; P < .0001). After adjustment for covariates, multivariable logistic regression analyses revealed that compared to the United States, Colombia had lower complication rates (2.8% vs 6.6%; odds ratio [OR], 0.41; 95% confidence interval [CI], 0.39-0.44; P < .0001) but higher mortality (0.44% vs 0.08%; OR, 8.92; 95% CI, 5.69-13.98; P < .0001) and failure to rescue (13.6% vs 1.0%; OR, 17.01; 95% CI, 10.66-27.16; P < .0001).

Conclusions: Despite lower rates of postoperative complications, in-hospital mortality after appendectomy was higher in Colombia than in the United States. This difference may be explained by higher rates of failure to rescue in the low-to-middle-income country (ie, decreased ability of Colombian hospitals to rescue patients from complications).

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Conflict of interest statement

Conflicts of Interests: See Disclosures at the end of the article.

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References

    1. Bratu I, Martens PJ, Leslie WD, Dik N, Chateau D, Katz A. Pediatric appendicitis rupture rate: disparities despite universal health care. J Pediatr Surg. 2008;43:1964–1969.
    1. Menachemi N, Chukmaitov A, Saunders C, Brooks RG. Hospital quality of care: does information technology matter? The relationship between information technology adoption and quality of care. Health Care Manage Rev. 2008;33:51–59.
    1. Weiss D, Eikemo TA. Technological innovations and the rise of social inequalities in health. Scand J Public Health. 2017;45:714–719.
    1. Meara JG, Leather AJ, Hagander L, et al. Global surgery 2030: evidence and solutions for achieving health, welfare, and economic development. Lancet. 2015;386:569–624.
    1. GlobalSurg Collaborative. Mortality of emergency abdominal surgery in high-, middle- and low-income countries. Br J Surg. 2016;103:971–988.