Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Mar 1;42(3):e61-e63.
doi: 10.1097/INF.0000000000003781. Epub 2022 Nov 29.

Use of Sotrovimab in 14 Children with COVID-19: A Single-center Experience

Sarina Kim Butzer  1 , Sandra Habbig  2 , Katrin Mehler  1 , Sophie Haumann  2 , Meike Meyer  3 , Norma Jung  4 , André Oberthür  1
Affiliations

Use of Sotrovimab in 14 Children with COVID-19: A Single-center Experience

Sarina Kim Butzer et al. Pediatr Infect Dis J. .

Abstract

Children affected by coronavirus disease 2019 (COVID-19) with preexisting comorbidities are at risk of complications. Monoclonal antibodies prevent severe COVID-19 courses in adults but data on children are scarce. Here we report on the use of Sotrovimab in 14 children at risk of severe disease treated at the University of Cologne Children's Hospital. Tolerability was good and no infusion-related reactions were seen.

PubMed Disclaimer

Conflict of interest statement

A.O. received lecture fees from AstraZeneca GmbH and Chiesi Pharmaceuticals. N.J. has received lecture fees from Gilead, Infectopharm, MSD, Bayer and Labor Stein and travel grants from Pfizer, Gilead, Basilea, Correvio, Pfizer and Novartis and grants from an observational study from Infectopharm. The other authors have no funding or conflicts of interest to disclose.

References

    1. Delahoy MJ, Ujamaa D, Whitaker M, et al. ; COVID-NET Surveillance Team. Hospitalizations associated with COVID-19 among children and adolescents - COVID-NET, 14 States, March 1, 2020-August 14, 2021. MMWR Morb Mortal Wkly Rep. 2021;70:1255–1260. - PMC - PubMed
    1. Tsankov BK, Allaire JM, Irvine MA, et al. . Severe COVID-19 infection and pediatric comorbidities: a systematic review and meta-analysis. Int J Infect Dis. 2021;103:246–256. - PMC - PubMed
    1. Haskin O, Ashkenazi-Hoffnung L, Ziv N, et al. . Serological response to the BNT162b2 COVID-19 mRNA vaccine in adolescent and young adult kidney transplant recipients. Transplantation. 2021;105:e226–e233. - PMC - PubMed
    1. Gupta A, Gonzalez-Rojas Y, Juarez E, et al. . Early treatment for Covid-19 with SARS-CoV-2 neutralizing antibody sotrovimab. N Eng J Med. 2021;385:1941–1950. - PubMed
    1. Götzinger F, Santiago-García B, Noguera-Julián A, et al. ; ptbnet COVID-19 Study Group. COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study. Lancet Child Adolesc Health. 2020;4:653–661. - PMC - PubMed

Publication types