[Comparative characteristics of the pathogenicity of 2 viruses of the family Rhabdoviridae for monkeys]

Abstract

Pathogenic properties of two viruses, Sowgrass and Barur, of the Rhabdoviridae family, isolated in different geographical zones were studied comparatively in green monkeys. These viruses showed different pathogenicity for monkeys by the intracerebral and subcutaneous routes of inoculation. Sowgrass virus had no manifest pathogenicity for monkeys, whereas Barur virus caused death of the animals in 5-6 days after intracerebral inoculation with typical localization of lesions in the brain. Subcutaneous inoculation of the animals produced no fatalities; slight lesions in organs and production of virus-neutralizing antibodies in the blood were observed.