Implementing clinical trial data sharing requires training a new generation of biomedical researchers

Ulrich Mansmann¹, Clara Locher², Fabian Prasser³, Tracey Weissgerber³, Ulrich Sax⁴, Martin Posch⁵, Evelyne Decullier⁶, Ioana A Cristea⁷, Thomas P A Debray^{8

9}, Leonhard Held¹⁰, David Moher^{11

12}, John P A Ioannidis^{13

14

15

16

17}, Joseph S Ross^{18

19

20}, Christian Ohmann²¹, Florian Naudet^{2

22}

Affiliations

¹ Ludwig-Maximilians University Munich, Institute for Medical Information Processing, Biometry, and Epidemiology, Munich, Germany. mansmann@ibe.med.uni-muenchen.de.
² Université Rennes, CHU Rennes, Inserm, Centre d'Investigation Clinique de Rennes (CIC1414), Service de Pharmacologie Clinique, Institut de Recherche en Santé, Environnement et Travail (Irset), UMR S 1085, EHESP, Rennes, France.
³ Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Berlin, Germany.
⁴ Department of Medical Informatics, University Medical Center, Göttingen, Germany.
⁵ Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
⁶ Hospices Civils de Lyon, Pôle Santé Publique, Unité de Recherche Clinique, Lyon, France.
⁷ Department of General Psychology, University of Padova, Padova, Italy.
⁸ Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
⁹ Smart Data Analysis and Statistics B.V., Utrecht, The Netherlands.
¹⁰ Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
¹¹ Center for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada.
¹² School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada.
¹³ Department of Medicine, Stanford University, Stanford, CA, USA.
¹⁴ Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.
¹⁵ Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
¹⁶ Department of Statistics, Stanford University, Stanford, CA, USA.
¹⁷ Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, CA, USA.
¹⁸ Section of General Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
¹⁹ Department of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA.
²⁰ Center for Outcomes Research and Evaluation, Yale New Haven Health System, New Haven, CT, USA.
²¹ European Clinical Research Infrastructure Network (ECRIN), Düsseldorf, Germany.
²² Institut Universitaire de France (IUF), Paris, France.

PMID: 36732626
DOI: 10.1038/s41591-022-02080-y

Free article

Implementing clinical trial data sharing requires training a new generation of biomedical researchers

Ulrich Mansmann et al. Nat Med. 2023 Feb.

Free article

. 2023 Feb;29(2):298-301.

doi: 10.1038/s41591-022-02080-y.

Authors

Affiliations

¹ Ludwig-Maximilians University Munich, Institute for Medical Information Processing, Biometry, and Epidemiology, Munich, Germany. mansmann@ibe.med.uni-muenchen.de.
² Université Rennes, CHU Rennes, Inserm, Centre d'Investigation Clinique de Rennes (CIC1414), Service de Pharmacologie Clinique, Institut de Recherche en Santé, Environnement et Travail (Irset), UMR S 1085, EHESP, Rennes, France.
³ Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Berlin, Germany.
⁴ Department of Medical Informatics, University Medical Center, Göttingen, Germany.
⁵ Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
⁶ Hospices Civils de Lyon, Pôle Santé Publique, Unité de Recherche Clinique, Lyon, France.
⁷ Department of General Psychology, University of Padova, Padova, Italy.
⁸ Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
⁹ Smart Data Analysis and Statistics B.V., Utrecht, The Netherlands.
¹⁰ Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
¹¹ Center for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada.
¹² School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada.
¹³ Department of Medicine, Stanford University, Stanford, CA, USA.
¹⁴ Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.
¹⁵ Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
¹⁶ Department of Statistics, Stanford University, Stanford, CA, USA.
¹⁷ Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, CA, USA.
¹⁸ Section of General Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
¹⁹ Department of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA.
²⁰ Center for Outcomes Research and Evaluation, Yale New Haven Health System, New Haven, CT, USA.
²¹ European Clinical Research Infrastructure Network (ECRIN), Düsseldorf, Germany.
²² Institut Universitaire de France (IUF), Paris, France.

PMID: 36732626
DOI: 10.1038/s41591-022-02080-y

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References

1. Koenig, F. et al. Biom. J. 57, 8–26 (2015). - DOI - PubMed
1. Localio, A. R. et al. Ann. Intern. Med. 168, 828–829 (2018). - DOI - PubMed
1. Taichman, D. B. et al. PLoS Med. 14, e1002315 (2017). - DOI - PubMed - PMC
1. Mello, M. M. et al. N. Engl. J. Med. 378, 2202–2211 (2018). - DOI - PubMed - PMC
1. Lin, D. et al. Sci. Data 7, 144 (2020). - DOI - PubMed - PMC

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Implementing clinical trial data sharing requires training a new generation of biomedical researchers

Affiliations

Implementing clinical trial data sharing requires training a new generation of biomedical researchers

Authors

Affiliations

References

MeSH terms

LinkOut - more resources

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