Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jan 17:10:1079232.
doi: 10.3389/fpubh.2022.1079232. eCollection 2022.

Pharmaceutical enterprises drug quality strategy Moran analysis considering government supervision and new media participation

Affiliations

Pharmaceutical enterprises drug quality strategy Moran analysis considering government supervision and new media participation

Yanping Xu et al. Front Public Health. .

Abstract

The improvement of drug quality requires not only the supervision of government, but also the participation of new media. Therefore, this paper considers the impact of government regulation and new media reports on pharmaceutical enterprises, constructs a Moran Process evolutionary game model, and analyzes the evolution trajectory of pharmaceutical enterprises' choice of drug quality improvement strategy and drug cost reduction strategy. We obtain the conditions for the two strategies to achieve evolutionary stability under the dominance of external factors and the dominance of expected returns. To verify the theoretical results, we conduct a numerical simulation by the software MATLAB 2021b. The results show that, first of all, when the government penalty is high, the drug quality improvement strategy tends to become an evolutionary stable solution, increasing the penalty amount will help promote the improvement of drug quality. What's more, when the government penalty is low and the new media influence is low, the drug cost reduction strategy is easier to dominate. The higher the new media influence, the higher the probability that pharmaceutical enterprises choose the drug quality improvement strategy. Thirdly, when the number of pharmaceutical enterprises is lower than a threshold, the drug quality improvement strategy is easier to dominate. Finally, the drug quality improvement strategy is dominant when the quality cost factor is low and the government penalty is high, the drug cost reduction strategy is dominant when the quality cost factor is high and the government penalty is low. Above all, this paper provides countermeasures and suggestions for the drug quality improvement of pharmaceutical enterprises in practice.

Keywords: Moran process; drug cost reduction strategy; drug quality improvement strategy; government supervision; new media participation.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Effect of the number of pharmaceutical enterprises on fixed point probability. This figure shows that under the dominance of external factors, the effect of the number of pharmaceutical enterprises on fixed point probability when considering different government penalty. (A) When F = 10.66, (B) When F = 1.066.
Figure 2
Figure 2
Effect of new media influence on fixed point probability. This figure shows that under the influence of external factors, the effect of new media influence on fixed point probability when considering different government penalty. (A) When F = 10.66, (B) When F = 1.066.
Figure 3
Figure 3
Effect of government penalty and new media influence. This figure shows the effect of the government penalty and the new media influence on the fixed-point probability under the dominance of external factors. (A) Fixed point probability N×ρQ, (B) Fixed point probability N×ρL.
Figure 4
Figure 4
Effect of the number of pharmaceutical enterprises on strategic choice. This figure shows that under the dominance of expected returns the effect of the number of pharmaceutical enterprises on the strategic choice when considering different government penalty. (A) When F = 5, (B) When F = 2.5, (C) When F = 1.
Figure 5
Figure 5
Effect of government penalty and new media influence on strategic choice. This figure shows the effect of government penalty and the new media influence on the choice of drug quality improvement strategy under the dominance of expected returns. (A) When q = 0.7, (B) When q = 0.4.

References

    1. Kyle MK. The alignment of innovation policy and social welfare: evidence from pharmaceuticals. Innovation Policy and the Economy. (2020) 20:95–123. 10.1086/705640 - DOI
    1. Swaminathan S. How to shape research to advance global health. Nature. (2019) 569:7–8. 10.1038/d41586-019-01235-1 - DOI - PubMed
    1. Swaminathan S, Pécoul B, Abdullah H. Reboot biomedical R&D in the global public interest. Nature. (2022) 602:207–10. 10.1038/d41586-022-00324-y - DOI - PubMed
    1. Paschke A, Dimancesco D, Vian T, Kohler JC, Forte G. Increasing transparency and accountability in national pharmaceutical systems. Bull World Health Organ. (2018) 96:782–91. 10.2471/BLT.17.206516 - DOI - PMC - PubMed
    1. Godman B, Fadare J, Kwon HY, Dias CZ, Kurdi A, Dias Godói IP, et al. Evidence-based public policy making for medicines across countries: findings and implications for the future. J Comp Eff Res. (2021) 10:1019–52. 10.2217/cer-2020-0273 - DOI - PubMed

Publication types

Substances