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. 2022 Oct 21;6(10):e22.00162.
doi: 10.5435/JAAOSGlobal-D-22-00162. eCollection 2022 Oct 1.

Prevalence of Vitamin D Deficiency in Patients With Charcot Arthropathy: A Single-Center Analysis

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Prevalence of Vitamin D Deficiency in Patients With Charcot Arthropathy: A Single-Center Analysis

Robert Daniel Kay et al. J Am Acad Orthop Surg Glob Res Rev. .

Abstract

Introduction: Vitamin D deficiency may be a potentially modifiable risk factor in patients with orthopaedic conditions including Charcot arthropathy. The purpose of this study was to determine the prevalence of vitamin D deficiency and insufficiency in patients with Charcot arthropathy.

Methods: All patients with Charcot arthropathy seen in our foot and ankle surgery clinic from January 2017 through June 2021 were screened for serum 25-hydroxyvitamin D levels. Patients were categorized as sufficient, insufficient, or deficient based on previously accepted guidelines. The prevalence of vitamin D deficiency and insufficiency was calculated.

Results: A total of 57 subjects were included in this study after meeting the inclusion criteria. Of these, 27 (47.4%) were found to be deficient in vitamin D, 21 (36.8%) were insufficient in vitamin D, and 9 (15.8%) were sufficient in vitamin D. Overall, 84.2% of the cohort was found to be either insufficient or deficient in vitamin D.

Conclusion: Vitamin D insufficiency and deficiency is highly prevalent in patients with Charcot arthropathy. As such, it is possible that this may play a role in the pathogenesis of Charcot arthropathy and may represent a potentially modifiable risk factor that could be optimized during the management of patients with Charcot arthropathy.

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Figures

Figure 1
Figure 1
Pie chart showing the prevalence of vitamin D deficiency, insufficiency, and sufficiency in patients with Charcot arthropathy.

References

    1. Looker AC, Johnson CL, Lacher DA, Pfeiffer CM, Schleicher RL, Sempos CT: Vitamin D status: United States, 2001-2006. NCHS Data Brief 2011;59:1-8. - PubMed
    1. Holick MF: The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention. Rev Endocr Metab Disord 2017;18:153-165. - PubMed
    1. Lee JS, Kim JW: Prevalence of vitamin D deficiency in postmenopausal high- and low-energy fracture patient. Arch Osteoporos 2018;13:109. - PubMed
    1. Maier GS, Jakob P, Horas K, Roth KE, Kurth AA, Maus U: Vitamin D deficiency in orthopaedic patients: A single center analysis. Acta Orthop Belg 2013;79:587-591. - PubMed
    1. Aujla RS, Allen PE, Ribbans WJ: Vitamin D levels in 577 consecutive elective foot & ankle surgery patients. Foot Ankle Surg 2019;25:310-315. - PubMed