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Randomized Controlled Trial
. 2023 Oct;27(5):1779-1785.
doi: 10.1007/s11325-023-02785-5. Epub 2023 Feb 3.

Efficacy of high-flow nasal oxygen during drug-induced sleep endoscopy in patients with obstructive sleep apnea

Sujung Park  1 , So Yeon Kim  1 , Hyun Joo Kim  2
Affiliations
Randomized Controlled Trial

Efficacy of high-flow nasal oxygen during drug-induced sleep endoscopy in patients with obstructive sleep apnea

Sujung Park et al. Sleep Breath. 2023 Oct.

Abstract

Purpose: High-flow nasal oxygenation (HFNO) can provide a low level of continuous positive airway pressure and alveolar recruitment. We aimed to compare the efficacy of pre-oxygenation with HFNO and low-flow nasal oxygenation (LFNO) during drug-induced sleep endoscopy (DISE).

Methods: In the LFNO group, preoxygenation was performed for 10 min at 3 L·min-1. In the HFNO group, preoxygenation was performed for 10 min at 30 L·min-1 at a fraction of inspired oxygen of 100% using the Optiflow device. From the start of sedative administration to the end of DISE, vital signs were monitored continuously. The primary outcome was the lowest oxygen saturation (SpO2) during DISE.

Results: Of 24 patients enrolled, 12 were randomly assigned to the LFNO and 12 to the HFNO groups. The prevalence of hypoxia events was 75% in the LFNO group and 58% in the HFNO group. The difference in lowest oxygen saturation between the two groups was not significant between the two groups (P=0.665). The lowest SpO2 during all procedures was comparable between the two groups (86.8 ± 6.5% in the LFNO group and 87.2 ± 8.0% in the HFNO group; P=0.912).

Conclusions: The findings suggest that HFNO may not be superior to LFNO as a preoxygenation tool to prevent hypoxia during DISE.

Keywords: Desaturation; Drug-induced sleep endoscopy; High-flow nasal oxygenation; Hypoxia; Sleep apnea.

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References

    1. Certal VF, Pratas R, Guimarães L et al (2016) Awake examination versus DISE for surgical decision making in patients with OSA: a systematic review. Laryngoscope 126:768–774. https://doi.org/10.1002/lary.25722 - DOI - PubMed
    1. Mirrakhimov AE, Sooronbaev T, Mirrakhimov EM (2013) Prevalence of obstructive sleep apnea in Asian adults: a systematic review of the literature. BMC Pulm Med 13:10. https://doi.org/10.1186/1471-2466-13-10 - DOI - PubMed - PMC
    1. Viana Ada C, Thuler LC, Araújo-Melo MH (2015) Drug-induced sleep endoscopy in the identification of obstruction sites in patients with obstructive sleep apnea: a systematic review. Braz J Otorhinolaryngol 81:439–446. https://doi.org/10.1016/j.bjorl.2015.01.007 - DOI - PubMed
    1. Atkins JH, Mandel JE (2018) Drug-induced sleep endoscopy: from obscure technique to diagnostic tool for assessment of obstructive sleep apnea for surgical interventions. Curr Opin Anaesthesiol 31:120–126. https://doi.org/10.1097/ACO.0000000000000543 - DOI - PubMed
    1. Cho JS, Soh S, Kim EJ et al (2015) Comparison of three sedation regimens for drug-induced sleep endoscopy. Sleep Breath 19:711–717. https://doi.org/10.1007/s11325-015-1127-9 - DOI - PubMed

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