Finding TB vaccine antigens: follow the TCRs
- PMID: 36735772
- DOI: 10.1126/sciimmunol.adg8281
Finding TB vaccine antigens: follow the TCRs
Abstract
TCR sequencing and analysis of predicted CDR3 structures were used to identify TCR similarity groups and the M. tuberculosis antigens they recognize that associate with infection control or progression.
Comment on
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T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection.Nat Med. 2023 Jan;29(1):258-269. doi: 10.1038/s41591-022-02110-9. Epub 2023 Jan 5. Nat Med. 2023. PMID: 36604540 Free PMC article.
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