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Review
. 2023 Mar;46(1):53-67.
doi: 10.1016/j.psc.2022.11.001. Epub 2022 Dec 27.

Cognitive Neuroscience of Obsessive-Compulsive Disorder

Laura B Bragdon  1 , Goi Khia Eng  2 , Nicolette Recchia  2 , Katherine A Collins  3 , Emily R Stern  2
Affiliations
Review

Cognitive Neuroscience of Obsessive-Compulsive Disorder

Laura B Bragdon et al. Psychiatr Clin North Am. 2023 Mar.

Abstract

Cognitive neuroscientific research has the ability to yield important insights into the complex neurobiological processes underlying obsessive-compulsive disorder (OCD). This article provides an updated review of neuroimaging studies in seven neurocognitive domains. Findings from the literature are discussed in the context of obsessive-compulsive phenomenology and treatment. Expanding our knowledge of the neural mechanisms involved in OCD could help optimize treatment outcomes and guide the development of novel interventions.

Keywords: Cognitive flexibility; Decision-making; Error monitoring; Goal-directed; Habit; Response inhibition; Reward; Threat conditioning.

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