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Review
. 2022 Nov 29;15(3):e24.
doi: 10.12786/bn.2022.15.e24. eCollection 2022 Nov.

Treatment of Adult Gliomas: A Current Update

Joo Ho Lee  1   2 , Chan Woo Wee  1   3
Affiliations
Review

Treatment of Adult Gliomas: A Current Update

Joo Ho Lee et al. Brain Neurorehabil. .

Abstract

Gliomas are the most common type of primary brain tumor in adults. Glioma treatment requires a multidisciplinary approach involving surgery, radiotherapy, and chemotherapy. Multiple trials have been conducted to establish the appropriate choice of treatment to achieve long-term survival and better quality of life. This review provides up-to-date evidence regarding treatment strategies for gliomas.

Keywords: Chemotherapy; Glioma; Radiotherapy; Surgery; Treatment.

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Conflict of interest statement

Conflict of Interest: The authors have no potential conflicts of interest to disclose.

References

    1. Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med. 2008;359:492–507. - PubMed
    1. Lee JH, Lee JH. The origin-of-cell harboring cancer-driving mutations in human glioblastoma. BMB Rep. 2018;51:481–483. - PMC - PubMed
    1. Lee JH, Lee JE, Kahng JY, Kim SH, Park JS, Yoon SJ, Um JY, Kim WK, Lee JK, Park J, Kim EH, Lee JH, Lee JH, Chung WS, Ju YS, Park SH, Chang JH, Kang SG, Lee JH. Human glioblastoma arises from subventricular zone cells with low-level driver mutations. Nature. 2018;560:243–247. - PubMed
    1. Figarella-Branger D, Appay R, Metais A, Tauziède-Espariat A, Colin C, Rousseau A, Varlet P. The 2021 WHO classification of tumours of the central nervous system. Ann Pathol. 2022;42:367–382. - PubMed
    1. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987–996. - PubMed