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Case Reports
. 2023 Feb 1;10(1):e00964.
doi: 10.14309/crj.0000000000000964. eCollection 2023 Jan.

Sarcoidosis of the Bile Duct

Muhammad Alsayid  1 , Ahmad Taftaf  2 , Khaled M Harmouch  3 , Anas Alabkaa  4 , Sam G Pappas  5 , Ajaypal Singh  1
Affiliations
Case Reports

Sarcoidosis of the Bile Duct

Muhammad Alsayid et al. ACG Case Rep J. .

Abstract

Sarcoidosis is an inflammatory disease that affects multiple organs. The lungs are the most commonly involved organs. Although a large proportion of patients with sarcoidosis have liver involvement, bile duct involvement is rare. Here, we present a case of a 56-year-old African American patient presented with painless jaundice because of extrahepatic bile duct sarcoidosis. Our diagnostic approach using endoscopic cholangioscopy with targeted biopsies confirmed the diagnosis. Multiple bile duct stent exchanges were performed to manage the bile duct stricture in addition to medical therapy.

Keywords: bile duct stricture; cholangioscopy; sarcoidosis.

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Figures

Figure 1.
Figure 1.
Endoscopic ultrasound showing an enlarged lymph node (arrows).
Figure 2.
Figure 2.
Endoscopic retrograde cholangiopancreatography showing a single severe stricture involving the common hepatic duct (arrow).
Figure 3.
Figure 3.
Cholangioscopy showing abnormal mucosa characterized by irregularity and nodularity without significant neovascularization.
Figure 4.
Figure 4.
Pathology slide showing reactive ductal epithelial cells with chronic inflammation and noncaseating granulomas (black arrows).
See this image and copyright information in PMC

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