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. 2021 Jul 13;14(2):e13.
doi: 10.12786/bn.2021.14.e13. eCollection 2021 Jul.

Associated Factors on Quality of Life in Patients with Parkinson's Disease

Yu Min Bang  1 , Yoojin Song  1 , Seo Jung Yun  2 , Han Gil Seo  2 , Won Hyuk Chang  1
Affiliations

Associated Factors on Quality of Life in Patients with Parkinson's Disease

Yu Min Bang et al. Brain Neurorehabil. .

Abstract

The objective of this study is to investigate the clinical and demographic factors that influence the quality of life in patients with Parkinson's disease (PD). This is a cross-sectional observational study of 47 patients in 2 hospitals with PD. All participants were asked to complete a disease-specific quality of life (QoL) questionnaire (PDQ-39). We gave a structured questionnaire interview and did a complete neurological examination on the same day. Additionally, we measured depression and dependency with the Geriatric Depression Scale-Short Form (GDS-SF) and the Korean version of the Modified Barthel Index (K-MBI). The PDQ-39 had a significant relationship with each motor part of the Unified Parkinson's Disease Rating Scale, the Korean Mini-Mental State Examination (K-MMSE), the GDS-SF, and the K-MBI (p < 0.05). The factors that independently contributed to the PDQ-39 scores were K-MMSE, GDS-SF, and K-MBI (p < 0.05). Factors having the greatest influence on the PDQ-39 were K-MBI, K-MMSE, and GDS-SF in that order. In addition, the mobility item in the K-MBI was independently a significant relating factor in the PDQ-39 (p < 0.05). These results demonstrated that dependency, especially with the mobility issue, was the greatest influence on the QoL in patients with PD.

Keywords: Independence; Parkinson's Disease; Quality of Life; Rehabilitation.

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Conflict of interest statement

Conflict of Interest: The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. Quality of life in participants.
Among the 8 PDQ-39 SI dimensions, the dimensions with the higher scores were the mobility, emotional, and stigma scores. In contrast, the domains with lower scores were social support, cognition and communication. PDQ-39 SI, Parkinson's Disease Questionnaire-39 Summary Index.
See this image and copyright information in PMC

References

    1. Reeve A, Simcox E, Turnbull D. Ageing and Parkinson's disease: why is advancing age the biggest risk factor? Ageing Res Rev. 2014;14:19–30. - PMC - PubMed
    1. Park JH, Kim DH, Kwon DY, Choi M, Kim S, Jung JH, Han K, Park YG. Trends in the incidence and prevalence of Parkinson's disease in Korea: a nationwide, population-based study. BMC Geriatr. 2019;19:320. - PMC - PubMed
    1. Rubenstein LM, DeLeo A, Chrischilles EA. Economic and health-related quality of life considerations of new therapies in Parkinson's disease. Pharmacoeconomics. 2001;19:729–752. - PubMed
    1. Kulisevsky J, Oliveira L, Fox SH. Update in therapeutic strategies for Parkinson's disease. Curr Opin Neurol. 2018;31:439–447. - PubMed
    1. Abbruzzese G, Marchese R, Avanzino L, Pelosin E. Rehabilitation for Parkinson's disease: Current outlook and future challenges. Parkinsonism Relat Disord. 2016;22(Suppl 1):S60–S64. - PubMed