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Review
. 2023 Feb;8(1):14-19.
doi: 10.1177/23971983221122673. Epub 2022 Sep 14.

Evaluation of hypertension in systemic sclerosis and systemic lupus erythematosus overlap

Erin Chew  1 , April Barnado  1 , Talat Alp Ikizler  2   3 , Roy Zent  2   3 , Tracy Frech  1   3
Affiliations
Review

Evaluation of hypertension in systemic sclerosis and systemic lupus erythematosus overlap

Erin Chew et al. J Scleroderma Relat Disord. 2023 Feb.

Abstract

Patients with systemic sclerosis and systemic lupus erythematosus serologies present a unique challenge to the clinician when hypertension is detected in the outpatient setting. Treatment choices for non-renal crisis hypertension are different for systemic sclerosis versus systemic lupus erythematosus. Urgent laboratory studies and, in the presence of certain symptoms, imaging assessment are indicated in systemic sclerosis and systemic lupus erythematosus overlap patients with systemic hypertension. Long-term assessment of systemic hypertension may be enhanced by advances in non-contrast imaging that serve as valuable biomarkers for progressive vasculopathy. In this review, the diagnostic approach to systemic sclerosis and systemic lupus erythematosus overlap patients presenting with hypertension is discussed.

Keywords: Systemic sclerosis; hypertension; renal crisis; systemic lupus erythematosus.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Assessment of hypertension in an SSc–SLE overlap patient. CBC: complete blood count; CMP: comprehensive metabolic profile; UA: urinalysis; eGFR: estimated glomerular filtration rate; LDH: lactate dehydrogenase.
See this image and copyright information in PMC

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