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. 2023 Apr;21(4):211-212.
doi: 10.1038/s41579-023-00861-x.

The WHO fungal priority pathogens list as a game-changer

Matthew C Fisher  1 , David W Denning  2   3
Affiliations

The WHO fungal priority pathogens list as a game-changer

Matthew C Fisher et al. Nat Rev Microbiol. 2023 Apr.

Abstract

Invasive fungal diseases are on the increase globally. The World Health Organization fungal priority pathogens list highlights fungi of critical or high importance to human health and provides pathways for action. The report calls for improved surveillance (diagnostics and antifungal resistance monitoring), research and innovation (implementation research) and public-health interventions.

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Conflict of interest statement

M.C.F. has been paid for talks on behalf of Gilead. D.W.D. and family hold Founder shares in F2G Ltd, a University of Manchester spin-out antifungal discovery company that is developing Olorofim, and share options in TFF Pharma. D.W.D. acts or has recently acted as a consultant to Pulmatrix, Pulmocide, Biosergen, TFF Pharmaceuticals, Pfizer, Omega, Novacyt, Rostra Therapeutics, MucPharm and Cipla. D.W.D. sat on the Data and Safety Monitoring Board for a SARS-CoV-2 vaccine trial and chairs a Data Review Committee for Pulmocide. In the past 3 years, D.W.D. has been paid for talks on behalf of Hikma, Gilead, BioRad, Basilea, Mylan and Pfizer. D.W.D. is a longstanding member of the Infectious Disease Society of America Aspergillosis Guidelines group, the European Society for Clinical Microbiology and Infectious Diseases Aspergillosis Guidelines group, and recently joined the One World Guideline for Aspergillosis.

References

    1. World Health Organization. WHO fungal priority pathogens list to guide research, development and public health action. WHOhttps://www.who.int/publications/i/item/9789240060241 (2022).
    1. Rajasingham R, et al. Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis. Lancet Infect. Dis. 2017;17:873–881. doi: 10.1016/S1473-3099(17)30243-8. - DOI - PMC - PubMed
    1. Bongomin F, Gago S, Oladele RO, Denning DW. Global and multi-national prevalence of fungal diseases — estimate precision. J. Fungi (Basel) 2017;3:57. doi: 10.3390/jof3040057. - DOI - PMC - PubMed
    1. Rhodes J, Fisher MC. Global epidemiology of emerging Candida auris. Curr. Opin. Microbiol. 2019;52:84–89. doi: 10.1016/j.mib.2019.05.008. - DOI - PubMed
    1. Fisher MC, et al. Tackling the emerging threat of antifungal resistance to human health. Nat. Rev. Microbiol. 2022;20:557–571. doi: 10.1038/s41579-022-00720-1. - DOI - PMC - PubMed

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