The Alzheimer's risk gene APOE modulates the gut-brain axis

Comment

Alfonso Martín-Peña et al. Nature. 2023 Feb.

. 2023 Feb;614(7949):629-630.

doi: 10.1038/d41586-023-00261-4.

No abstract available

Keywords: Alzheimer's disease; Immunology; Microbiology; Neurodegeneration.

Comment on

ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy.
Seo DO, O'Donnell D, Jain N, Ulrich JD, Herz J, Li Y, Lemieux M, Cheng J, Hu H, Serrano JR, Bao X, Franke E, Karlsson M, Meier M, Deng S, Desai C, Dodiya H, Lelwala-Guruge J, Handley SA, Kipnis J, Sisodia SS, Gordon JI, Holtzman DM. Seo DO, et al. Science. 2023 Jan 13;379(6628):eadd1236. doi: 10.1126/science.add1236. Epub 2023 Jan 13. Science. 2023. PMID: 36634180 Free PMC article.

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