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. 1987 May;51(2):145-52.
doi: 10.1111/j.1469-1809.1987.tb01056.x.

The human placental alkaline phosphatase gene and related sequences map to chromosome 2 band q37

D Martin  1 , D F Tucker, P Gorman, D Sheer, N K Spurr, J Trowsdale
Affiliations

The human placental alkaline phosphatase gene and related sequences map to chromosome 2 band q37

D Martin et al. Ann Hum Genet. 1987 May.

Abstract

A human placental alkaline phosphatase (PLAP) cDNA was isolated from a lambda gt 10 library of the cell line HEp-2. Southern blots probed with a fragment of the cDNA clone showed that the human genome may contain more than one PLAP-related sequence. The PLAP probe showed person-to-person variation in banding pattern with a number of enzymes. Using a panel of human/rodent somatic cell hybrids the PLAP sequences were mapped to chromosome 2. In situ hybridization confirmed this assignment and localized the gene(s) to chromosome 2 band q37.

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