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. 2023 Feb 7:103:adv00861.
doi: 10.2340/actadv.v103.4804.

Serum Interleukin-13 and Caspase 8 are Elevated in Prurigo Nodularis

Teresa Ju  1 , Angelina Labib  1 , Leigh Nattkemper  1 , Sarah Engle  2 , Autum Auxier  2 , Nathan Hahn  2 , Sean Sissons  2 , Jonathan T Sims  2 , Zhe Sun  3 , Angela J Okragly  2 , Gil Yosipovitch  4
Affiliations

Serum Interleukin-13 and Caspase 8 are Elevated in Prurigo Nodularis

Teresa Ju et al. Acta Derm Venereol. .
No abstract available

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Conflict of interest statement

GY has served as an advisory board member, investigator and/or received consulting fees from Galderma, Pfizer, Sanofi Regeneron, Novartis, Eli Lilly, Kiniksa, Vellus and Cell Dex. SE, AA, SS, JTS, ZS and AO are all employees and potentially stockholders of Eli Lilly. All other authors have no additional conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1
Volcano plot of proteomic assays showing analytes with > 1.3-fold changes that were significant (qval < 0.05). Blue circles represent analytes significantly reduced in prurigo nodularis (PN) vs healthy controls (HC). Red circles represent analytes significantly elevated in PN vs HC. “S” indicates single-plex assay. Protein markers with missing data frequency > 80% were removed from Olink data analysis (IL20RA, IL2RB, IL1 alpha, IL2, IL22RA1, Beta-NGF, IL13, ARTN, IL20, IL33, LIF, NRTN, IL5). FLT3L: fms-related tyrosine kinase 3 ligand. IL13_S: interleukin 13 from single-plex analysis. TRAIL: tumour necrosis factor-related apoptosis-inducing ligand. IL17C: interleukin-17 C.
See this image and copyright information in PMC

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