Renal findings in rheumatoid arthritis: clinical aspects of 132 necropsies
- PMID: 3675007
- PMCID: PMC1002227
- DOI: 10.1136/ard.46.9.658
Renal findings in rheumatoid arthritis: clinical aspects of 132 necropsies
Abstract
Renal abnormalities in 132 necropsied patients with rheumatoid arthritis were studied. Clinical findings before death included extra-articular manifestations of the disease (86% of patients), systemic vasculitis (6%), and uraemia (23%). Necropsy findings included nephrosclerosis (90%), systemic vasculitis (14%) with kidney involvement in 8%, amyloidosis (11%), membranous glomerulopathy (8%), and focal glomerular disease (8%). Association with clinical data suggests that both rheumatoid and non-rheumatoid disease may play a part in the cause of these abnormalities.
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