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. 2022 Dec 9;4(49):1093-1096.
doi: 10.46234/ccdcw2022.221.

Dissemination of Antibiotic Resistance Genes Among Patients with Diarrhea - Freetown, Sierra Leone, 2018

Xia Chen  1   2 , Enmin Zhang  1   2 , Michael K Abdulai  2 , Alie Brima Tia  2 , Esther Debora Ngegba  2 , Jianhai Yin  3   2 , Songtao Xu  4   2 , Lili Wang  5 , Xiaoping Dong  4   5 , Doris Harding  6 , Biao Kan  1   2
Affiliations

Dissemination of Antibiotic Resistance Genes Among Patients with Diarrhea - Freetown, Sierra Leone, 2018

Xia Chen et al. China CDC Wkly. .

Abstract

What is already known about this topic?: Antibiotic resistance (AR) is a serious public health threat worldwide. However, the AR and antibiotic resistance genes (ARGs) data from West Africa, especially from Sierra Leone, are limited.

What is added by this report?: The study revealed ARGs' common dissemination, and multiplex antibiotic resistance genes in one sample. Genes bla NDM and bla OXA -48-like were first discovered in Sierra Leone.

What are the implications for public health practice?: Basic information is provided for AR research and surveillance and highlights that effective AR surveillance among diarrhea patients is necessary for Sierra Leone and West Africa.

Keywords: Antibiotic Resistance Genes; Diarrhea; Dissemination.

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