Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Feb 6;2023(2):rjad034.
doi: 10.1093/jscr/rjad034. eCollection 2023 Feb.

Primary pulmonary meningioma with associated multiple micronodules: a case report and literature review

Bei Yang  1 , Jingxin Qiu  2
Affiliations
Case Reports

Primary pulmonary meningioma with associated multiple micronodules: a case report and literature review

Bei Yang et al. J Surg Case Rep. .

Abstract

Primary pulmonary meningioma (PPM) is a rare and benign slow growing tumor with good prognosis. It often presents as an asymptomatic, well-circumscribed, solitary pulmonary nodule. Wedge resection is the management of choice for both diagnosis and treatment. Here, we report one case of PPM with increased fluorodeoxyglucose (FDG) uptake and associated micronodules, which was clinically suspicious for malignancy. The patient was a 60-year-old female who presented with persistent shortness of breath for 1 year. Chest computed tomography showed a 1.5-cm well-circumscribed homogenous nodule in the left upper lobe with increased FDG uptake and multiple smaller well-circumscribed micronodules scattered in both lungs. Left upper lobe wedge resection confirmed the diagnosis of PPM. PPM can deceptively mimic malignancy, so recognizing this rare entity and including it in the differential diagnoses of pulmonary nodules, especially with avid uptake of FDG, is crucial to avoid misdiagnosis and overtreatment.

Keywords: FDG PET; multiple micronodules; primary pulmonary meningioma.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Chest CT images of the lesions (A) left upper lobe lesion (1.5 cm) before surgery on 15 December 2021; (B) left upper lobe lesion after surgery on 21 June 2022; (C) right upper lobe lesion (0.5 cm) on 15 December 2021; (B) right upper lobe lesion on 21 June 2022; there is no change on the size.
Figure 2
Figure 2
(A) H&E section (200×) shows whorls formation and pseudo-nuclear inclusions; tumor cells are positive for EMA (B), SSTR2a (C) and PR (D) (200×).
See this image and copyright information in PMC

References

    1. Umana GE, Scalia G, Vats A, Pompili G, Barone F, Passanisi M, et al. . Primary extracranial meningiomas of the head and neck. Life (Basel) 2021;11:942. - PMC - PubMed
    1. Kemnitz P, Spormann H, Heinrich P. Meningioma of lung: first report with light and electron microscopic findings. Ultrastruct Pathol 1982;3:359–65. - PubMed
    1. Han D, Deng H, Liu Y. Primary pulmonary meningiomas: report of two cases and review of the literature. Pathol Res Pract 2020;216:153232. - PubMed
    1. Incarbone M, Ceresoli GL, Di Tommaso L, Cappuzzo F, Inzirillo F, Infante M, et al. . Primary pulmonary meningioma: report of a case and review of the literature. Lung Cancer 2008;62:401–7. - PubMed
    1. Moran CA, Hochholzer L, Rush W, Koss MN. Primary intrapulmonary meningiomas. A clinicopathologic and immunohistochemical study of ten cases. Cancer 1996;78:2328–33. - PubMed

Publication types