Changing careers: Skin pathogen evolves to infect the bloodstream
- PMID: 36758515
- DOI: 10.1016/j.chom.2023.01.005
Changing careers: Skin pathogen evolves to infect the bloodstream
Abstract
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) rose to clinical dominance decades ago and predominantly manifested as skin and soft-tissue infections (SSTIs). These clones were distinct from those causing hospital acquired (HA-MRSA) infections. Dyzenhaus et al. describe the evolutionary changes necessary for CA-MRSA clones to cause bloodstream infections (BSIs).
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation.Cell Host Microbe. 2023 Feb 8;31(2):228-242.e8. doi: 10.1016/j.chom.2022.12.003. Epub 2023 Jan 20. Cell Host Microbe. 2023. PMID: 36681080 Free PMC article.
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