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Randomized Controlled Trial
. 2023 Feb;10(1):e002214.
doi: 10.1136/openhrt-2022-002214.

Mobile-phone text messaging to promote ideal cardiovascular health in women

Affiliations
Randomized Controlled Trial

Mobile-phone text messaging to promote ideal cardiovascular health in women

Monica Acevedo et al. Open Heart. 2023 Feb.

Abstract

Objective: Ideal cardiovascular health (CVH) was developed to promote CVH as a key component of primordial prevention. Mobile short message service (SMS) is useful for improving health behaviours. We aim to test the effectiveness of SMS intervention in women to improve CVH.

Methods: In a single-blinded, randomised, controlled study, 620 women, aged 35-70 years, without cardiovascular disease, were enrolled in SMS intervention versus no SMS. CVH metrics by self-report, and biochemical laboratory, anthropometric and blood pressure measurements were collected during home visits at baseline and 9 months. Women were categorised as having poor (0-2), intermediate (3-4) or ideal (5-7) CVH according to the number of ideal CVH metrics. Participants were randomised 1:1 to SMS intervention versus control. SMS was sent every 5-6 days for 9 months. The primary outcome was the difference in the proportion of women with ideal CVH between SMS and control groups at 9 months. Rates of intermediate CVH, poor CVH and each of the seven ideal CV health metrics at 9 months were key secondary endpoints.

Results: At 9 months, there was no significant difference between groups for the primary outcome (16.3% at baseline and 13.3% at 9 months, and 10.1% and 11.1%, in SMS and control groups, respectively, adjusted RR 1.0; 95% CI 0.6 to 1.6). Similarly, there were no significant differences between groups for the key secondary endpoints. SMS had an acceptance rate of 94.9%.

Conclusions: Behavioural SMS intervention did not improve rates of ideal CVH in women, despite being feasible and well received.

Trial registration number: 6377.

Keywords: Global Health; Outcome Assessment, Health Care; RISK FACTORS.

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Conflict of interest statement

Competing interests: MA has served on an advisory board for AstraZeneca, Bayer, Novo Nordisk, Boehringer, Tecnofarma, Axon Pharma, Novartis and has received fees for speaking from AstraZeneca, Boehringer Ingelheim, Bayer, Novo Nordisk, Tecnofarma, TEVA Pharmaceuticals, Abbott, Axon Pharma, Elli Lilly. PV has served on advisory boards for Axon Pharma, Novo Nordisk, Boehringer Ingelheim, Novartis, and has received fees for speaking from: Boehringer Ingelheim, AstraZeneca Novo Nordisk, Axon Pharma, Abbott, Bayer and Tecnofarma, Organon, Teva Pharmaceuticals and fees for being the principal investigator for the following Clinical Studies: Horizon (Novartis)/ Victorion Prevent (Novartis).

Figures

Figure 1
Figure 1
Participant flow diagram.

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