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Case Reports
. 2023 Jan;50(1):87-89.

[A Case of Conversion Surgery after Long-Term Chemotherapy for Pancreatic Cancer with Peritoneal Metastasis]

[Article in Japanese]
Michihiro Enoki  1 , Kunihito Gotoh, Kenji Sakai, Reishi Toshiyama, Kiminori Yanagisawa, Kenji Kawai, Masaaki Miyo, Yusuke Takahashi, Takuya Hamakawa, Takashi Doi, Atsushi Takeno, Takeshi Katoh, Koji Takami, Motohiro Hirao
Affiliations
  • PMID: 36759995
Case Reports

[A Case of Conversion Surgery after Long-Term Chemotherapy for Pancreatic Cancer with Peritoneal Metastasis]

[Article in Japanese]
Michihiro Enoki et al. Gan To Kagaku Ryoho. 2023 Jan.

Abstract

A 66-year-old woman was referred to the gastroenterology division of our hospital due to elevation of serum CEA level. Contrast-enhanced CT showed a hypovascular tumor at the body of pancreas. She was diagnosed with pancreatic cancer by EUS-FNA. By laparotomy, we found white nodules on mesentery and abdominal wall, which were diagnosed as peritoneal metastasis. After systemic chemotherapy with 9 courses of gemcitabine(GEM)plus nab-paclitaxel(PTX)and 30 courses of mFOLFIRINOX, the tumor had shrunk and serum CA19-9 level were remarkably decreased. Distal pancreatectomy was performed as conversion surgery. Pathological analysis revealed no remnant cancer cells in the primary tumor or the lymph nodes, confirming a pCR. S-1 was started as adjuvant chemotherapy, and she remains alive without recurrence 8 months after surgery.

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