The role of sacituzumab govitecan in hormone receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer
- PMID: 36760255
- PMCID: PMC9906197
- DOI: 10.21037/atm-22-5266
The role of sacituzumab govitecan in hormone receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer
Keywords: Antibody drug conjugates; overall survival (OS); targeted therapy.
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://atm.amegroups.com/article/view/10.21037/atm-22-5266/coif). JPL has received research funding from Kazia therapeutics and consulting fees from Minerva Biotechnologies. The other author has no conflicts of interest to declare.
Comment on
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Sacituzumab Govitecan in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer.J Clin Oncol. 2022 Oct 10;40(29):3365-3376. doi: 10.1200/JCO.22.01002. Epub 2022 Aug 26. J Clin Oncol. 2022. PMID: 36027558 Clinical Trial.
References
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- Breast Cancer Group, Branch of Oncologist, Chinese Medical Doctor Association ; International Medical Exchange Society. Chinese expert consensus of antibody-drug conjugate toxicity management for breast cancer. Zhonghua Zhong Liu Za Zhi 2022;44:913-27. - PubMed
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- de Lartigue J. Next-Generation Antibody-Drug Conjugates Make Their Mark in Breast Cancer. OncLive 2022;23.
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- Vidula N, Yau C, Rugo HS. Trop2 gene expression (Trop2e) in primary breast cancer (BC): Correlations with clinical and tumor characteristics. J Clin Oncol 2017;35:abstr 1075.
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