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. 2023 Jun;280(6):2653-2661.
doi: 10.1007/s00405-023-07841-0. Epub 2023 Feb 10.

A systematic review of validated assessments methods for head and neck lymphedema

Coralie R Arends #  1 , Josephine E Lindhout #  2   3 , Lisette van der Molen  2   4 , Erica A Wilthagen  5 , Michiel W M van den Brekel  6   7   8 , Martijn M Stuiver  2   9   10
Affiliations

A systematic review of validated assessments methods for head and neck lymphedema

Coralie R Arends et al. Eur Arch Otorhinolaryngol. 2023 Jun.

Abstract

Purpose: This systematic review aimed to provide a comprehensive overview of the validity and reliability of existing measurement instruments for quantifying head and neck lymphedema.

Methods: Four databases were searched on January 31st, 2022. The COnsensus-based Standards for selecting health Measurement INstruments (COSMIN) checklists were used for the risk of bias (ROB) assessment.

Results: Out of 3362 unique records, eight studies examined the reliability and validity of five measurement instruments of which one patient reported outcome. The Patterson scale for internal lymphedema and the patient reported head and neck external lymphedema and fibrosis (LIDS-H&N) demonstrated validity and reliability. For external lymphedema, none of the instruments had good reliability for all measuring points.

Conclusion: There is a lack of sufficiently reliable and valid measurement instruments for external head and neck lymphedema. The Patterson scale and the patient reported LIDS-H&N seem reliable for clinical practice and research.

Keywords: Head and neck cancer; Lymphedema; Measurement; Reliability; Validity.

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Conflict of interest statement

The authors have no conflicts of interest.

Figures

Fig. 1
Fig. 1
PRISMA flow diagram. aMEDLINE (PubMed), Embase (OVID), SCOPUS, and PEDro
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References

    1. Murphy BA, Gilbert J. Dysphagia in head and neck cancer patients treated with radiation: assessment, sequelae, and rehabilitation. Semin Radiat Oncol. 2009;19:35–42. doi: 10.1016/j.semradonc.2008.09.007. - DOI - PubMed
    1. Nguyen NP, Sallah SMD, et al. Combined chemotherapy and radiation therapy for head and neck malignancies: quality of life issues. Cancer. 2002;94:1131–1141. doi: 10.1002/cncr.10257. - DOI - PubMed
    1. Jaguar GC, Prado JD, et al. Clinical features and preventive therapies of radiation-induced xerostomia in head and neck cancer patient: a literature review. Appl Cancer Res. 2017 doi: 10.1186/s41241-017-0037-5. - DOI
    1. Wijers OB, Levendag PC, et al. Patients with head and neck cancer cured by radiation therapy: a survey of the dry mouth syndrome in long-term survivors. Head Neck. 2002;24:737–747. doi: 10.1002/hed.10129. - DOI - PubMed
    1. Dirix P, Nuyts S, Van den Bogaert W. Radiation-induced xerostomia in patients with head and neck cancer: a literature review. Cancer. 2006;107:2525–2534. doi: 10.1002/cncr.22302. - DOI - PubMed

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