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. 1987 Nov;55(5):421-31.
doi: 10.1007/BF00367458.

Intestinal iron absorption and mucosal transferrin in rats subjected to hypoxia

K R Osterloh  1 , R J Simpson, S Snape, T J Peters
Affiliations

Intestinal iron absorption and mucosal transferrin in rats subjected to hypoxia

K R Osterloh et al. Blut. 1987 Nov.

Abstract

Three days hypoxia (0.5 atm) increased the haemoglobin and haematocrit values in rats paralleled by enhanced intestinal iron absorption. The destination of recently-absorbed iron was primarily the erythropoietic system, viz. bone marrow, spleen and red cells. Total plasma transferrin, was increased by 30%, but no significant changes in mucosal transferrin were found. No increase in labelling of mucosal transferrin by absorbed iron was observed. These results suggest that mucosal transferrin does not play a major role in the regulation of intestinal iron absorption in hypoxia.

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References

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