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Case Reports
. 2023 Feb 10;23(1):63.
doi: 10.1186/s12883-023-03068-y.

Eclampsia with hypothyroidism complicated with posterior reversible encephalopathy syndrome-a case report

Xuejing Yin  1 , Yu Duan  2 , Lifang Zhang  3 , Zhichao Feng  1 , Caixia Yin  4 , Sujie Zhu  1 , Jinhua Chen  5   6   7 , Xinsen Peng  8
Affiliations
Case Reports

Eclampsia with hypothyroidism complicated with posterior reversible encephalopathy syndrome-a case report

Xuejing Yin et al. BMC Neurol. .

Abstract

Background: Posterior reversible encephalopathy syndrome (PRES) is a rare neurological disorder with complex physiopathological mechanisms that have not been fully understood. Early identification is of great prognostic significance, of which the symptoms and radiological abnormalities can be completely reversed. If the diagnosis and treatment are delayed, ischemia and massive infarction may be developed in some patients. Posterior reversible encephalopathy syndrome (PRES) has been reported mainly in association with postpartum eclampsia, which have been rarely reported, while the association with hypothyroidism has not been reported at home or abroad.

Case presentation: Here we report on a pregnant 29-year-old with multipara and a chief complication of hypothyroidism. She presented in the emergency department with frequent attacks of severe headache symptoms resulting from reversible cerebral vasoconstriction syndrome (RCVS), accompanied with prenatal eclampsia. PRES was determined by radiological examination.

Conclusion: To the best of our knowledge, this is the first case of PRES complicated by hypothyroidism and prepartum eclampsia.Clinicians should be alert for the co-occurence of eclampsia, PRES, and RCVS when patients have convulsions after a typical throbbing headache. Moreover, regular monitoring of thyroid function during pregnancy should also occupy certain special attention.

Keywords: Case report; Eclampsia; Hypothyroidism; Posterior reversible encephalopathy syndrome; Reversible cerebral vasoconstriction syndrome.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Brain MRI in a patient with Eclampsia with Hypothyroidism Complicated with Posterior Reversible Encephalopathy Syndrome (PRES). Legend: diffusion restriction on the diffusion-weighted sequences and apparent dispersion coefficient (Both sides)
See this image and copyright information in PMC

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