Biological function of resveratrol and its application in animal production: a review

Abstract

With the prohibition of antibiotics in feed, plant functional substances have been widely studied as feed additives. Resveratrol, a natural stilbene, and a non-flavonoid polyphenol found in plants, possesses antioxidant, anti-inflammatory, and metabolic regulatory features. Resveratrol generated intense scientific and public interest, primarily due to its widely reported ability to prevent cancer, delay aging and alleviate related metabolic diseases. Recently, resveratrol has been studied and applied as a feed additive in animal production. This review focuses on the outline of the absorption and metabolism and biological functions of resveratrol and summarizes the application of dietary resveratrol in animal production up to the present, including pigs, poultry, and ruminants. In pigs, dietary resveratrol improved intestinal health, mitochondrial function, meat quality, and more. In poultry, studies have shown that dietary resveratrol improves growth performance and meat and egg quality and alleviates heat stress induced adverse effects. There are few studies on dietary resveratrol in ruminants; however previous studies have indicated that dietary resveratrol increases nutrient digestibility and reduces methane emissions in sheep. It is hoped that this review could provide a specific theoretical basis and research ideas for the research and application of resveratrol.

Keywords: Animal production; Biological function; Health; Pigs; Poultry; Resveratrol; Ruminants.

Fig. 1

The important research process of resveratrol

Fig. 2

The chemical structure of resveratrol

Fig. 3

The metabolic regulation effects of resveratrol via SIRT1, AMPK, and PGC-1α [12, 13, 84]. SIRT1, sirtuin 1; AMPK, AMP-activated protein kinase; PGC-1α, peroxisome proliferators-activated receptor gamma coactivator-1 alpha

Fig. 4

The summary of beneficial effects of dietary resveratrol in animal production