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Editorial
. 2023 Jan-Dec;22(1):207-209.
doi: 10.1080/14760584.2023.2179486.

Toward an effective Staphylococcus vaccine: why have candidates failed and what is the next step?

Chih-Ming Tsai  1 , Jr Caldera  2 , Irshad A Hajam  1 , George Y Liu  1   3
Affiliations
Editorial

Toward an effective Staphylococcus vaccine: why have candidates failed and what is the next step?

Chih-Ming Tsai et al. Expert Rev Vaccines. 2023 Jan-Dec.
No abstract available

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Conflict of interest statement

Declaration of interest

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or material discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or mending, or royalties.

References

    1. Centers for Disease Control and Prevention: Antibiotic Resistance Threats in the United States, 2019. Atlanta, GA: Centers for Disease Control and Prevention; Available at: https://www.cdc.gov/drugresistance/pdf/threatsreport/2019-ar-threats-rep...., (2019).
    1. wright AE. Notes on the Treatment of Furunculosis, Sycosis, and Acne by the Inoculation of a Staphylococcus aureus Vaccine. Lancet, (159), 874–884 (1902).
    1. Armentrout EI, Liu GY, Martins GA. T Cell Immunity and the Quest for Protective Vaccines against Staphylococcus aureus Infection. Microorganisms, 8(12) (2020). - PMC - PubMed
    1. Miller LS, Fowler VG, Shukla SK, Rose WE, Proctor RA. Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms. FEMS Microbiol Rev, 44(1), 123–153 (2020). - PMC - PubMed
    1. Tsai CM, Caldera JR, Hajam IA et al. Non-protective immune imprint underlies failure of Staphylococcus aureus IsdB vaccine. Cell Host Microbe, 30(8), 1163–1172 e1166 (2022). - PMC - PubMed

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