Editorial

. 2023 Jan 18;15(3):581.

doi: 10.3390/cancers15030581.

Elucidation of the Role of SMAD4 in Epithelial-Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of DPC4 Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

Hendrik Ungefroren^{1

2

3}, Björn Konukiewitz², Rüdiger Braun⁴, Ulrich Friedrich Wellner⁴, Tobias Keck⁴, Jens-Uwe Marquardt^{1

3}

Affiliations

¹ First Department of Medicine, University Hospital Schleswig-Holstein (UKSH), Campus Lübeck, D-23538 Lübeck, Germany.
² Institute of Pathology, University Hospital Schleswig-Holstein, Campus Kiel, D-24105 Kiel, Germany.
³ Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, D-23538 Lübeck, Germany.
⁴ Department of Surgery, University Hospital Schleswig-Holstein, Campus Lübeck, D-23538 Lübeck, Germany.

PMID: 36765537
PMCID: PMC9913373
DOI: 10.3390/cancers15030581

Editorial

Elucidation of the Role of SMAD4 in Epithelial-Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of DPC4 Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

Hendrik Ungefroren et al. Cancers (Basel). 2023.

. 2023 Jan 18;15(3):581.

doi: 10.3390/cancers15030581.

Authors

Hendrik Ungefroren^{1

2

3}, Björn Konukiewitz², Rüdiger Braun⁴, Ulrich Friedrich Wellner⁴, Tobias Keck⁴, Jens-Uwe Marquardt^{1

3}

Affiliations

¹ First Department of Medicine, University Hospital Schleswig-Holstein (UKSH), Campus Lübeck, D-23538 Lübeck, Germany.
² Institute of Pathology, University Hospital Schleswig-Holstein, Campus Kiel, D-24105 Kiel, Germany.
³ Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, D-23538 Lübeck, Germany.
⁴ Department of Surgery, University Hospital Schleswig-Holstein, Campus Lübeck, D-23538 Lübeck, Germany.

PMID: 36765537
PMCID: PMC9913373
DOI: 10.3390/cancers15030581

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is the 4th leading cause of cancer-related mortality worldwide, with a 5-year-survival rate below 10% that is the lowest of all cancer types [...].

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Conflict of interest statement

The authors declare no conflict of interest.

Cited by

Polarization of Cancer-Associated Macrophages Maneuver Neoplastic Attributes of Pancreatic Ductal Adenocarcinoma.
Lin HJ, Liu Y, Caroland K, Lin J. Lin HJ, et al. Cancers (Basel). 2023 Jul 5;15(13):3507. doi: 10.3390/cancers15133507. Cancers (Basel). 2023. PMID: 37444617 Free PMC article. Review.
Significance of TP53, CDKN2A, SMAD4 and KRAS in Pancreatic Cancer.
Stefanoudakis D, Frountzas M, Schizas D, Michalopoulos NV, Drakaki A, Toutouzas KG. Stefanoudakis D, et al. Curr Issues Mol Biol. 2024 Mar 23;46(4):2827-2844. doi: 10.3390/cimb46040177. Curr Issues Mol Biol. 2024. PMID: 38666907 Free PMC article. Review.

References

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Elucidation of the Role of SMAD4 in Epithelial-Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of DPC4 Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

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Elucidation of the Role of SMAD4 in Epithelial-Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of DPC4 Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

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