Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Jan 17;20(3):1682.
doi: 10.3390/ijerph20031682.

Low-Grade Inflammation and Role of Anti-Inflammatory Diet in Childhood Obesity

Ewelina Polak-Szczybyło  1
Affiliations
Review

Low-Grade Inflammation and Role of Anti-Inflammatory Diet in Childhood Obesity

Ewelina Polak-Szczybyło. Int J Environ Res Public Health. .

Abstract

At present, pediatric obesity is a significant public health concern. We have seen a surge of disorders that are obesity-related, e.g., insulin resistance (IR), type 2 diabetes mellitus (T2DM), high blood pressure, heart disease, stroke, cancer, non-alcoholic fatty liver disease (NAFLD), autoimmune disorders and many more. The mechanisms linking these diseases to excess body weight are related to low-grade inflammation (LGI). Although there is a limited number of studies assessing this immune process in childhood obesity, they indicate its significant importance for the health of future generations. There is a need for more research into the prevention and treatment of low-grade inflammation in childhood. The aim of this review is to present and discuss the process of "cold" inflammation, and its impact on health and anti-inflammation nutrition. A diet rich in anti-inflammatory nutrients may be the key to maintaining health, as well as recovery.

Keywords: anti-inflammatory diet; childhood obesity; children; low-grade inflammation; metabolic syndrome.

PubMed Disclaimer

Conflict of interest statement

The author declares no conflict of interest.

Figures

Figure 1
Figure 1
Mechanism of low-grade inflammation in obesity.
Figure 2
Figure 2
Possible consequences of low-grade inflammation in childhood obesity.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. World Health Organization Home Page. [(accessed on 15 October 2022)]. Available online: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.
    1. Stavridou A., Kapsali E., Panagouli E., Thirios A., Polychronis K., Bacopoulou F., Psaltopoulou T., Tsolia M., Sergentanis T.N., Tsitsika A. Obesity in Children and Adolescents during COVID-19 Pandemic. Children. 2021;12:135. doi: 10.3390/children8020135. - DOI - PMC - PubMed
    1. Versini M., Jeandel P.Y., Rosenthal E., Shoenfeld Y. Obesity in autoimmune diseases: Not a passive bystander. Autoimmun. Rev. 2014;13:981–1000. doi: 10.1016/j.autrev.2014.07.001. - DOI - PubMed
    1. Calle E.E., Rodriguez C., Walker-Thurmond K., Thun M. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N. Engl. J. Med. 2003;348:1625–1638. doi: 10.1056/NEJMoa021423. - DOI - PubMed
    1. Deckelbaum R.J., Williams C.L. Childhood Obesity: The Health Issue. Obes. Res. 2001;9:239S–243S. doi: 10.1038/oby.2001.125. - DOI - PubMed

Substances