Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Jan 31;16(3):1242.
doi: 10.3390/ma16031242.

The Safety of Fluoride Compounds and Their Effect on the Human Body-A Narrative Review

Affiliations
Review

The Safety of Fluoride Compounds and Their Effect on the Human Body-A Narrative Review

Adam Lubojanski et al. Materials (Basel). .

Abstract

Fluoride is one of the elements commonly present in the human environment. Due to its characteristics, it is very widely used in medicine, dentistry, industry or agriculture. On the other hand, its universality possesses a real threat to the human body in the form of acute and chronic poisoning. The aim of this paper is to characterize the properties of fluoride and its effects on the human body, as well as the sources of its occurrence. Particular emphasis is placed on the safety of its use and optimal dosage intake, which prevents accumulation and reduces its potential side effects. The positive effect of proper fluoride supply is widely described. In order to avoid overdose, it is best to consult a specialist to properly select the dosage.

Keywords: acute and chronic poisoning; caries prevention; caries risk; fluoride; fluorosis.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Fluoride supply sources.
Figure 2
Figure 2
A scheme of different stages of fluorosis.
Figure 3
Figure 3
A scheme of a tooth with a filling containing fluoride ions that are released in the oral cavity.

References

    1. Kanduti D., Sterbenk P. Artnik, and fluoride: A review of use and effects on health. Mater. Socio Med. 2016;28:133. doi: 10.5455/msm.2016.28.133-137. - DOI - PMC - PubMed
    1. Sikorska-Jaroszyńska M.H., Czelej G. Fluor w Stomatologii i Medycynie. Wydawnictwo Czelej; Lublin, Poland: 2000.
    1. Dhar V., Bhatnagar M. Physiology and toxicity of fluoride. Indian J. Dent. Res. 2009;20:350. doi: 10.4103/0970-9290.57379. - DOI - PubMed
    1. Ozsvath D.L. Fluoride and environmental health: A review. Rev. Environ. Sci. Biotechnol. 2009;8:59–79. doi: 10.1007/s11157-008-9136-9. - DOI
    1. Jha S.K., Mishra V.K., Sharma D.K., Damodaran T. Fluoride in the environment and its metabolism in humans. Rev. Environ. Contam. Toxicol. 2011;211:121–142. - PubMed

LinkOut - more resources