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Review
. 2023 Jun:50 Suppl 1:104-108.
doi: 10.1002/mp.16272. Epub 2023 Feb 17.

A persistent belief in radiopharmaceutical therapy

Affiliations
Review

A persistent belief in radiopharmaceutical therapy

George Sgouros. Med Phys. 2023 Jun.

Abstract

Imaging and dosimetry physics are essential to the long-term success of radiopharmaceutical therapy (RPT), a cancer treatment modality that can deliver potent cytotoxic radiation to disseminated cancer cells. This is a review of my personal journey in this field.

Keywords: dosimetry; imaging; radionuclides.

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References

REFERENCES

    1. Bigler RE, Sgouros G. Biological analysis and dosimetry for 15O-labeled O2, CO2, and CO gases administered continuously by inhalation. J Nucl Med. 1983;24(5):431-437.
    1. Sgouros G, Barest G, Thekkumthala J, et al. Treatment planning for internal radionuclide therapy: three-dimensional dosimetry for nonuniformly distributed radionuclides. J Nucl Med. 1990;31(11):1884-1891.
    1. Bigler RE, Zanzonico PB, Cosma M, Sgouros G. Radiolabeled Monoclonal Antibodies for Imaging and Therapy. Springer; 1988:409-429.
    1. Sgouros G, Ballangrud AM, Jurcic JG, et al. Pharmacokinetics and dosimetry of an alpha-particle emitter labeled antibody: 213Bi-HuM195 (anti-CD33) in patients with leukemia. J Nucl Med. 1999;40(11):1935-1946.
    1. Jurcic JG, Larson SM, Sgouros G, et al. Targeted alpha-particle immunotherapy for myeloid leukemia. Blood. 2002;100(4):1233-1239.

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