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. 2023 Jun;53(4):104673.
doi: 10.1016/j.idnow.2023.104673. Epub 2023 Feb 11.

Symptoms of Long-COVID 1-Year after a COVID-19 outbreak among sailors on a French aircraft carrier

A Perisse  1 , F De Cacqueray  2 , D Delarbre  3 , H Marsaa  1 , C Bergmann  4 , V Da Silva  5 , A Bronstein  6 , N Paleiron  6 , N Menoud  7 , J Cobola  7 , C Verret  8 , A Mayet  9 , O Bylicki  10
Affiliations

Symptoms of Long-COVID 1-Year after a COVID-19 outbreak among sailors on a French aircraft carrier

A Perisse et al. Infect Dis Now. 2023 Jun.

Abstract

Objectives: While persistent symptoms have been reported after the coronavirus disease-2019 (COVID-19), long-term data on outpatients with mild COVID-19 are lacking. The objective was to describe symptoms persisting for 12 months.

Methods: This prospective cohort study on 1767 sailors of an aircraft carrier in which a Covid-19 outbreak occurred during a mission in April 2020 described predefined self-reported symptoms of Long-COVID at 6, 9 and 12 months. Logistic-regression analyses were used to identify correlates for Long-COVID at months 6, 9 and 12.

Results: Among the 641 participants, 619 (35%) completed at least one follow-up questionnaire (413 COVID-positive and 206 COVID-negative). Symptoms of Long-COVID were reported by 53.7%, 55.2% and 54.3% of COVID-positive participants vs 31.2%, 23.3% and 40.0% in COVID-negative patients, at 6 (p <.002), 9 (p <.002) and 12 months (p =.13), respectively. The most frequent symptoms reported were concentration and memory difficulties, asthenia and sleep disorders.

Conclusion: In this study more than half of COVID-positive outpatients reported persistent symptoms up to 12 months post-quarantine. These findings suggests that all patients, including those with mild disease, can be affected by Long-COVID. A lack of difference at 12 months with COVID-negative patienys prompts caution. The symptoms of Long-COVID are so non-specific that they may be viewed as the consequence of multiple intercurrent factors.

Keywords: Aircraft-carrier; Long term symptoms; SARS-CoV2; Symptoms of Long-COVID.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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