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. 2022 Sep 30;10(3):191-196.
doi: 10.2478/jtim-2022-0036. eCollection 2022 Sep.

Metabolic Adaptation in Lactation: Insulin-dependent and -independent Glycemic Control

Ling Fu  1 , Maria A Ramos-Roman  2 , Yingfeng Deng  1
Affiliations

Metabolic Adaptation in Lactation: Insulin-dependent and -independent Glycemic Control

Ling Fu et al. J Transl Int Med. .
No abstract available

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Conflict of interest statement

Conflict of Interest None declared.

Figures

Figure 1
Figure 1
Insulin-independent glycemic control during lactation augments glucose uptake and utilization in mammary glands. Simultaneously, glucose uptake in insulin-responsive tissues such as the liver, adipose tissues, and skeletal muscle, that is, insulin-dependent glucose uptake and utilization, shows a reduction compared to the nonlactating state. ER stress and the UPR in mammary glands and adipose tissues during lactation may play a key role in coordination of the maternal metabolic remodeling. ER: endoplasmic reticulum; UPR: unfolded protein response.
See this image and copyright information in PMC

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